Long-term survival after an aggressive surgical approach in patients with breast cancer hepatic metastases

Annals of Surgical Oncology
Georges VlastosJean-Nicolas Vauthey

Abstract

Metastatic breast cancer is generally believed to be associated with a poor prognosis. Therapeutic advances over the past two decades, however, have resulted in improved outcomes for selected patients with limited metastatic disease. Between March 1991 and October 2002, 31 patients had hepatic resection for breast cancer metastases limited to the liver. Clinical and pathologic data were collected prospectively from breast and hepatobiliary databases. Median age of patients was 46 years (range, 31 to 70). Liver metastases were solitary in 20 patients and multiple in 11 patients. Median size of the largest liver metastasis was 2.9 cm (range, 1 to 8). Major liver resections (three or more segments resected) were performed in 14 patients, whereas minor resections (fewer than three segments resected) with or without radiofrequency ablation (RFA) were performed in 17 patients. No postoperative mortality occurred. Of the 31 patients, 27 (87%) received either preoperative or postoperative systemic therapy as treatment for metastatic disease. The median survival was 63 months; a single patient died within 12 months of hepatic resection. The overall 2- and 5-year survival rates were 86% and 61%, respectively, whereas the 2- and 5-year di...Continue Reading

References

Mar 1, 1978·American Journal of Surgery·J H Foster
Jan 1, 1990·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·S M O'ReillyR D Rubens
May 1, 1987·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J W ZinserG Fraschini
Feb 1, 1981·Cancer·N A SamaanR Martin
Oct 1, 1995·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·D EliasM Spielmann
Jan 1, 1994·Journal of Surgical Oncology·S SchneebaumJ P Minton
Nov 1, 1995·Annals of Surgical Oncology·G M FuhrmanM S Roh
Apr 4, 2000·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·M PocardR Salmon
Feb 7, 2001·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·S M MaksanC Herfarth
Jul 13, 2001·Annales de chirurgie·M PocardR J Salmon
Jun 29, 2002·Nuclear Medicine Communications·C RoséN Avril
May 9, 2003·Surgical Oncology Clinics of North America·Courtney L Scaife, Steven A Curley
May 30, 2003·The Oncologist·S Eva SingletaryGabriel N Hortobágyi
Jul 17, 2003·British Journal of Cancer·L WyldA J Evans

❮ Previous
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Citations

Feb 20, 2014·HPB Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery·Malte WeinrichBettina M Rau
Aug 26, 2014·Langenbeck's Archives of Surgery·Timothy L FitzgeraldEmmanuel E Zervos
Nov 24, 2006·Annals of Surgery·René AdamDenis Castaing
May 14, 2011·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Yee Chung Cheng, Naoto T Ueno
Sep 22, 2007·AJR. American Journal of Roentgenology·C T SofocleousK T Brown
Mar 28, 2008·Surgery Today·Jean LubranoMichel Scotté
Mar 12, 2013·World Journal of Surgery·F PolistinaG Ambrosino
Feb 10, 2010·Annals of Surgical Oncology·Katrin HoffmannPeter Schemmer
May 7, 2013·Journal of Cancer Research and Clinical Oncology·Y DittmarU Settmacher
Jun 26, 2008·Cardiovascular and Interventional Radiology·Tobias F JakobsMaximilian F Reiser
Nov 14, 2007·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·T SalmanS Mills
Oct 16, 2013·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·P MarianiR J Salmon
Feb 2, 2013·Critical Reviews in Oncology/hematology·W KhodariUNKNOWN AROME (Association of Radiotherapy and Oncology of the Mediterranean arEa; www.aromecancer.org)
Jun 12, 2012·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·G A M van WalsumUNKNOWN Dutch Liver Surgeons Group
Aug 17, 2011·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Mathieu D'HondtRéal Lapointe
Mar 23, 2011·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Maria A CasseraPaul D Hansen
Mar 12, 2008·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Dominique Elias, Daniela Di Pietroantonio
May 25, 2011·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·M BergenfeldtD Nielsen
Mar 30, 2010·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Céline BourgierRodrigo Arriagada
Jul 14, 2009·Surgical Oncology·Emilie LermitePatrick Pessaux
Aug 30, 2008·Journal of Vascular and Interventional Radiology : JVIR·Jourdan E StuartDaniel B Brown
Apr 9, 2008·Seminars in Oncology·Cletus A Arciero, Elin R Sigurdson
Oct 16, 2007·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·D Goéré, D Elias
May 15, 2007·Journal of Vascular and Interventional Radiology : JVIR·Affaan K BangashRiad Salem
May 26, 2007·International Journal of Radiation Oncology, Biology, Physics·Douglas M ColdwellCharles W Nutting
Feb 14, 2007·Journal of Vascular and Interventional Radiology : JVIR·Gowthaman GunabushanamSushma Bhatnagar
Aug 27, 2010·Journal of Surgical Oncology·Mechteld C de JongTimothy M Pawlik
Aug 10, 2011·Journal of Surgical Oncology·Masakuni NoguchiTakeo Kosaka
Jul 4, 2007·Surgical Oncology Clinics of North America·Eugene A Choi, Eddie K Abdalla
Aug 16, 2005·Radiologic Clinics of North America·Larissa BragaRichard C Semelka
May 13, 2015·Future Oncology·Petros CharalampoudisChristos Markopoulos
Jul 12, 2011·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Terence C ChuaDavid L Morris
Feb 2, 2011·International Journal of Surgery·Mohammad HowladerMohamed Rela
Mar 31, 2015·Gynécologie, obstétrique & fertilité·N LotersztajnR Rouzier
Apr 19, 2011·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Gero WienersJens Ricke
Aug 27, 2014·Journal of Vascular and Interventional Radiology : JVIR·Andrew C GordonRobert J Lewandowski
Jul 31, 2013·The American Journal of Pathology·Natascia MarinoPatricia S Steeg

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