Long-term survival after aortic valve replacement in octogenarians and high-risk subgroups

European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
Per MølstadStein Rynning

Abstract

The increasing age in the population and improvements in the treatment options for aortic valvular disease have resulted in a considerable rise in the number of elderly patients being admitted for conventional aortic valve surgery. Recently, transcatheter aortic valve implantation (TAVI) has been developed as a less invasive treatment option. However, both open heart surgery and transcatheter treatment have serious complications. Thus, the knowledge of contemporary results of conventional surgery is important in guiding treatment allocation. From the database at Feiring Heart Clinic, 1525 patients were identified who had undergone aortic valve replacement from 1999 to 2010; of these, 361 patients were more than 80 years of age. The population was followed for all-cause mortality until March 2011, with special reference to the age group older than 80 years and other high-risk subsets. The short-term mortality was 2.2% in the whole population and 3.9% in octogenarians. Five-year survival was 83.1 and 68.1%, respectively. In the high-risk subgroup of patients with a logistic EuroSCORE above 20%, the equivalent figures were 4.2 and 72.7%. Contemporary results after conventional aortic valve surgery are excellent in both short- and ...Continue Reading

References

Aug 4, 1999·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·F RoquesL Thulin
May 20, 2003·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Philippe MichelUNKNOWN EuroSCORE Project Group
Feb 5, 2005·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Frédéric CollartDominique Metras
Nov 28, 2006·The Annals of Thoracic Surgery·Ramdas G PaiPadmini Varadarajan
Feb 20, 2007·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Philippe KolhRaymond Limet
Oct 11, 2008·Scandinavian Cardiovascular Journal : SCJ·Per Mølstad
Nov 27, 2008·European Heart Journal·Brigitte R OsswaldEugene H Blackstone
Feb 24, 2009·Lancet·Blase A Carabello, Walter J Paulus
Apr 22, 2009·The Annals of Thoracic Surgery·Sergey LeontyevFriedrich W Mohr
Feb 2, 2010·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Ines FlorathJuergen Ennker
Jul 6, 2010·The Journal of Thoracic and Cardiovascular Surgery·Marco Di EusanioRoberto Di Bartolomeo
Oct 22, 2010·The New England Journal of Medicine·Martin B LeonUNKNOWN PARTNER Trial Investigators
Mar 17, 2011·The Thoracic and Cardiovascular Surgeon·M GaudinoG Possati
Jun 7, 2011·The New England Journal of Medicine·Craig R SmithUNKNOWN PARTNER Trial Investigators
Jul 5, 2011·Journal of Cardiothoracic and Vascular Anesthesia·Bart M J A KoeneAndré J van Zundert
Sep 29, 2011·Journal of Cardiac Surgery·Nicolas NikolaidisSunil K Ohri
Oct 11, 2011·The Annals of Thoracic Surgery·Thierry LanganayAlain Leguerrier

❮ Previous
Next ❯

Citations

May 9, 2012·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Manuel J Antunes
Apr 29, 2015·Scandinavian Cardiovascular Journal : SCJ·Per Mølstad
Jul 15, 2015·Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology·António TralhãoJosé Pedro Neves
Oct 4, 2014·Revista clínica española·Y CarrascalC Ortega
Sep 10, 2014·The Annals of Thoracic Surgery·Tomasz A TimekLawrence H Patzelt
Dec 19, 2013·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·Aiman AlassarMarjan Jahangiri
Aug 12, 2014·Journal of Cardiovascular Medicine·Silvia SaffiotiFilippo Crea
Apr 13, 2021·The Journal of Thoracic and Cardiovascular Surgery·Jean PorterieSiamak Mohammadi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
Francesco OnoratiAlessandro Mazzucco
European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
Enrico Ferrari
The Journal of Thoracic and Cardiovascular Surgery
Cary W AkinsAd Hoc Liaison Committee for Standardizing Definitions of Prosthetic Heart Valve Morbidity
© 2021 Meta ULC. All rights reserved