Long-term survival after blood transfusion: a population based study in the North of England

Transfusion
Jonathan P WallisCatherine E Chapman

Abstract

Blood transfusion may transmit infectious diseases with long incubation periods. Estimation of the risks of transmission of such disease requires know-ledge of long-term survival of transfused patients. No such information is available in the UK, where there is particular concern about possible transmission by trans-fusion of variant CJD. Information on survival after transfusion and demographics was collected for all patients transfused during June 1994 in a population of 2.9 million served by a single blood center. A total of 2899 patients were transfused with 10,760 units of RBCs (99% of RBCs issued during the study period). Follow-up to death or 5 years was completed for 98.2 percent, and 46.9 percent of all transfusion recipients were alive at 5 years; 41 percent of transfused RBC units and 36 percent of transfused FFP were given to patients who were alive at 5 years. Median age at transfusion was 67 years (mean, 60.9 years). Shorter patient survival was associated with increasing patient age, increasing numbers of RBC units transfused, trans-fusion of plasma or PLTs, and nonsurgical indications for transfusion. Posttransfusion survival is lower than estimated in previous decades in other countries. This is probably due to...Continue Reading

References

Jun 1, 1994·Transfusion·E C Vamvakas, H F Taswell
Mar 10, 2001·Transfusion·E TynellA Björkman
Jun 7, 2002·Lancet·P SimmondsR S Tedder
Jul 31, 2002·Transfusion·Eleftherios C Vamvakas, Rosalyn Goldstein
Oct 12, 2002·BMJ : British Medical Journal·A W WellsJ P Wallis
Oct 22, 2002·The Journal of General Virology·Nora HunterFiona Houston
Jul 26, 2003·Transfusion Medicine Reviews·Eleftherios C Vamvakas

❮ Previous
Next ❯

Citations

Jan 11, 2011·Transactions of the Royal Society of Tropical Medicine and Hygiene·Jose P Moura NetoMarilda S Goncalves
Feb 9, 2007·Journal of the Royal Society, Interface·Paul ClarkeAzra C Ghani
May 19, 2009·Anesthesia and Analgesia·Stephen D SurgenorUNKNOWN Northern New England Cardiovascular Disease Study Group
Mar 21, 2007·Emerging Infectious Diseases·Klaus DietzJohannes Löwer
Nov 19, 2010·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Margreet C van EerdMaria A de Peuter
Aug 27, 2009·Transfusion Medicine·M S S Namen-LopesA B F Carneiro-Proietti
Feb 3, 2007·Transfusion Medicine·T J CobainK Titlestad
Aug 5, 2008·Transfusion·Mads Kamper-JørgensenHenrik Hjalgrim
Jan 23, 2008·Transfusion·France GauvinHeather Hume
Dec 20, 2005·Vox Sanguinis·H V New
Jun 18, 2010·Transfusion·Steven KleinmanDana Devine
Aug 24, 2010·Vox Sanguinis·B A Borkent-RavenB A van Hout
Nov 13, 2010·Transfusion Medicine·J P Wallis
Jul 29, 2010·Transfusion·M Alba BoschUNKNOWN Catalonian Blood Transfusion Epidemiology Study Group
May 18, 2012·Transfusion·Thelma T GoncalezUNKNOWN NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II) and International Component
Jul 31, 2013·Transfusion·Wim de KortTanneke Marijt-van der Kreek
Jul 30, 2010·The Annals of Thoracic Surgery·Martin CzernyMichael Grimm
Nov 27, 2004·Transfusion clinique et biologique : journal de la Société française de transfusion sanguine·V JossetP Czernichow
Sep 30, 2006·Transfusion Medicine Reviews·Dorothy StainsbyUNKNOWN SHOT Steering Group
Apr 25, 2006·The Annals of Thoracic Surgery·Colleen Gorman KochEugene H Blackstone
Dec 7, 2005·Thrombosis Research·Ioannis BatsisAchilles Anagnostopoulos
Apr 23, 2016·Transfusion Medicine·S L MorleyUNKNOWN EASTR study group
Mar 13, 2016·Transfusion Medicine·S L MorleyUNKNOWN EASTR study group
Aug 1, 2007·Circulation·Timothy J Gardner
Jun 10, 2006·The Journal of Trauma·Sheila MacLennan, Lorna M Williamson

❮ Previous
Next ❯

Related Concepts

Related Feeds

Babesiosis

Babesiosis is caused by parasites of the genus babesia, which are transmitted in nature by the bite of an infected tick. Discover the latest research on babesiosis here.

Bovine Spongiform Encephalopathy (MDS)

Bovine spongiform encephalopathy is a neurodegenerative disease belonging to the transmissible spongiform encephalopathies, a group of diseases including sheep scrapie and human Creutzfeldt-Jakob disease. Here is the latest research.

Bovine Spongiform Encephalopathy

Bovine spongiform encephalopathy is a neurodegenerative disease belonging to the transmissible spongiform encephalopathies, a group of diseases including sheep scrapie and human Creutzfeldt-Jakob disease. Here is the latest research.