Long-term survival after curative resection for pancreatic ductal adenocarcinoma. Clinicopathologic analysis of 5-year survivors

Annals of Surgery
K C ConlonM F Brennan

Abstract

The authors reviewed the clinicopathologic characteristics of patients who underwent resection with curative intent for ductal adenocarcinoma of the pancreas between 1983 and 1989. Recent studies have demonstrated a reduction in the morbidity and mortality of pancreatic resection and improvement in the actuarial 5-year survival for patients with resected ductal adenocarcinoma. Resection with curative intent was performed on 118 of 684 patients (17%) with pancreatic cancer admitted to the authors' institution. Clinical, demographic, treatment, and pathologic variables were analyzed. The original material for all cases was reviewed; nonductal cancers were excluded. The head of the gland was the predominant tumor site (n = 102), followed by the body (n = 9), and tail (n = 7). Seventy-two percent of the patients underwent pancreaticoduodenectomies, 15% underwent total pancreatectomies, 10% underwent distal pancreatectomies, and 3% underwent distal subtotal pancreatectomies. Operative mortality was 3.4%. Median survival was 14.3 months after resection compared with 4.9 months if patients did not undergo resection (p < 0.0001). Twelve patients survived 5 years after surgery (10.2% overall actual 5-year survival rate). Three of the tu...Continue Reading

References

Aug 1, 1992·Archives of Surgery·B W MiedemaD Ilstrup
Jan 1, 1991·American Journal of Surgery·J L CameronJ Coleman
Nov 1, 1990·Journal of Surgical Oncology·G J HarrisA B Cruz
Apr 1, 1990·Archives of Surgery·R J DoerrL M Flint
Dec 1, 1987·American Journal of Surgery·M S Lea, L H Stahlgren
Sep 1, 1987·Annals of Surgery·M M ConnollyF Lowenstein
Aug 1, 1988·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·H S Wu, A G Little
Nov 1, 1987·Cancer·B Gudjonsson
Jan 1, 1986·American Journal of Surgery·P A GraceW P Longmire
Jan 1, 1995·CA: a Cancer Journal for Clinicians·P A WingoS Bolden
Mar 1, 1995·Archives of Surgery·C Fernández-del CastilloA L Warshaw
Jan 1, 1993·American Journal of Surgery·R J Geer, M F Brennan

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Citations

May 7, 2002·International Journal of Cancer. Journal International Du Cancer·Kei HiraokaHiroyuki Katoh
Apr 26, 2001·Journal of Surgical Oncology·P E Queneau, M Usel
Aug 6, 2011·Archivum Immunologiae Et Therapiae Experimentalis·Robert SłotwińskiZdzisław Wójcik
Mar 20, 2009·Cardiovascular and Interventional Radiology·Loukas ThanosDimitrios A Kelekis
Apr 6, 2006·Cancer Causes & Control : CCC·Rosemary D CressElizabeth A Holly
Feb 14, 2006·Clinical & Experimental Metastasis·Chang F QuBarry J Allen
Mar 6, 2009·Journal of Genetic Counseling·Zoe K LewisVickie L Venne
May 8, 2007·Journal of Thrombosis and Thrombolysis·Beste OzbenAhmet Oktay
Apr 17, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Rory L SmootMichael B Farnell
Sep 6, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Michael G HousePeter J Allen
Sep 20, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Kimberly Moore DalalDaniel G Coit
Oct 24, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Jürgen TreckmannChristoph E Broelsch
Nov 21, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Cristina R FerronePeter J Allen
Mar 19, 2008·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Jeannine BachmannMarc E Martignoni
Feb 19, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Laura BeyerVincent Moutardier
Feb 19, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Chang Moo KangWoo Jung Lee
Sep 14, 2010·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Douglas D BensonCarlton C Barnett
Dec 14, 2011·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Sohei SatoiA-Hon Kwon
May 26, 2005·Current Gastroenterology Reports·Christopher M HalloranJohn P Neoptolemos
Dec 16, 2003·American Journal of Surgery·Russell G Postier
Oct 1, 2013·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Mazin O HamedGareth Morris Stiff
Apr 29, 1999·American Journal of Surgery·M Huguier, N P Mason
Jul 19, 2001·The Surgical Clinics of North America·A M Cooperman
Jul 19, 2001·The Surgical Clinics of North America·R T Poon, S T Fan
Jul 19, 2001·The Surgical Clinics of North America·R Wagman, A Grann
May 15, 2002·International Journal of Radiation Oncology, Biology, Physics·Hiroyuki ShinchiTakashi Aikou
Aug 12, 2003·International Journal of Radiation Oncology, Biology, Physics·Oliver MickeUlrich Schäfer
Oct 15, 2003·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·E BriasoulisP Fumoleau
Jul 31, 2001·Surgical Oncology·C M HalloranE Costello
Jan 1, 1997·Surgical Oncology·J R Howe, K C Conlon
Apr 9, 1999·Journal of the American College of Surgeons·N B MerchantM F Brennan
Mar 28, 2002·Drug Discovery Today·Kathryn Senior
Jul 19, 2003·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·M FalconiP Pederzoli
Jun 10, 2008·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Lisa KimGuang-Yu Yang
Mar 27, 2013·Nature Reviews. Gastroenterology & Hepatology·Raghuwansh P SahSuresh T Chari
Apr 8, 1998·The British Journal of Surgery·M J McCarthyJ P Neoptolemos
Jul 4, 1998·The British Journal of Surgery·V DiCarloE Villa

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