Long-term survival and quality of life after extracorporeal life support: a 10-year report

European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
Daniele CamboniClaudius Diez

Abstract

Information is lacking about long-term survival and quality of life (QOL) after treating patients on extracorporeal life support. Outcome data were assessed by phone interviews, a QOL analysis using the EuroQol 5-dimensions questionnaire and a retrospective inquiry of the Regensburg ECMO Registry database for the decade 2006-2015. A statistical analysis was obtained by comparing patients with a cardiosurgical intervention (CS = 189 patients) with those without (w/oCS = 307 patients). Survival to discharge in the w/oCS group was higher than that in the CS group (w/oCS: 41.7% vs CS: 29.5%; P  = 0.004). A Kaplan-Meier analysis showed a significant difference between both groups in favour of patients w/oCS (log rank P  = 0.02). This difference was no longer statistically significant after propensity score matching ( P  = 0.07). The 1- and 2-year survival rates of discharged patients were 67% and 50% in the w/oCS group vs 60% and 45% in the CS group (log rank P  = 0.29). Eighty-two patients answered the QOL questionnaire after a mean follow-up time of 4.2 ± 2.9 years. A total of 75% could handle their daily life; 57% were not limited in their usual activities. Mobility impairment was noted in 50%; 25% returned to work or school. The...Continue Reading

References

Jan 1, 1995·Research in Developmental Disabilities·D Felce, J Perry
Aug 9, 2001·Annals of Medicine·R Rabin, F de Charro
Apr 26, 2005·Archives of Medical Research·Omer AydemirErtugrul Koroglu
Oct 31, 2008·Heart, Lung & Circulation·Silvana F MarascoBenno Ihle
May 27, 2010·Journal of Clinical Nursing·Michelle A Kelly, Sharon McKinley
Oct 23, 2012·Critical Care : the Official Journal of the Critical Care Forum·Carol L HodgsonVin Pellegrino
Nov 5, 2013·The Journal of Thoracic and Cardiovascular Surgery·Bryan G MaxwellJim K Wong
May 31, 2014·Seminars in Cardiothoracic and Vascular Anesthesia·Stephen A EsperKenichi A Tanaka
Sep 25, 2014·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Brian W GrayRobert H Bartlett
Oct 4, 2014·Journal of the American College of Cardiology·Robert StretchPramod Bonde
Dec 30, 2014·Journal of Cardiothoracic and Vascular Anesthesia·Ashleigh XiePaul Forrest
Jan 16, 2015·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·M BullingerM Augustin
Oct 8, 2015·The American Journal of Cardiology·Brett J CarrollJosé P Garcia

❮ Previous
Next ❯

Citations

Mar 11, 2018·BMC Health Services Research·Annemieke Oude Lansink-HartgringUNKNOWN Dutch ECLS study group
Feb 6, 2019·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Lukasz KmiecDaniele Camboni
Feb 1, 2020·European Heart Journal. Acute Cardiovascular Care·Salla Jäämaa-HolmbergJyri Lommi
Jun 27, 2019·JAAPA : Official Journal of the American Academy of Physician Assistants·Michelle Freeman, Marshall Lee
Jan 10, 2018·Expert Review of Cardiovascular Therapy·Sebastian NudingRoland Prondzinsky
Dec 12, 2018·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Salla Jäämaa-HolmbergJyri Lommi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.