Long-term survival with complete remission after hepatic arterial infusion chemotherapy for liver metastasis from gastric cancer: a case report

World Journal of Surgical Oncology
Takahiro ToyokawaKosei Hirakawa

Abstract

We report a case of long-term survival with complete remission after hepatic arterial infusion chemotherapy (HAIC) for liver metastasis from gastric cancer. A 62-year-old man underwent radical distal gastrectomy with D2 lymphadenectomy for an advanced gastric cancer. Solitary liver metastasis in the S2/3 segment was detected 26 months after initial surgery. The patient underwent HAIC with systemic chemotherapy. Serum CEA levels rapidly decreased, and CT scan showed disappearance of the tumor with complete clinical response 8 months after HAIC. HAIC was performed 83 times in total, until the hepatic artery proper was adequately obstructed. No severe adverse effects were observed during HAIC treatment. The patient is still disease-free without further chemotherapy more than 12 years after HAIC. Our experience suggests that HAIC should be considered as a treatment option in patients with resectable liver metastasis from gastric cancer. However, further studies are needed to verify the validity of HAIC for resectable liver metastasis from gastric cancer.

References

Feb 15, 2000·The British Journal of Surgery·C H YooJ S Min
Apr 18, 2000·Archives of Surgery·L A LambertR J Barth
May 30, 2001·American Journal of Surgery·S AmbiruN Nakajima
Dec 26, 2001·Annals of Surgery·Keiichi OkanoHajime Maeta
Oct 20, 2004·Annals of Surgery·Michael D'AngelicaMartin S Karpeh
Dec 24, 2005·Journal of Vascular and Interventional Radiology : JVIR·Koichiro YamakadoKan Takeda
Jun 23, 2007·World Journal of Surgical Oncology·Hitoshi OjimaHiroyuki Kuwano
Mar 12, 2008·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Ken ShirabeTakashi Nagaie
Feb 23, 2011·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Hiroyuki NaraharaYuh Sakata
Feb 26, 2011·International Journal of Cancer. Journal International Du Cancer·Jacques FerlayDonald Maxwell Parkin
May 17, 2011·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·UNKNOWN Japanese Gastric Cancer Association
May 17, 2011·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·UNKNOWN Japanese Gastric Cancer Association
Feb 11, 2012·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Mattia GaranciniFabrizio Romano
Feb 23, 2012·World Journal of Surgery·Claus W SchildbergA Perrakis
Sep 12, 2013·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Yasuhiro KoderaMichitaka Fujiwara
Sep 21, 2013·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Florian LordickDavid Ilson
Dec 25, 2013·Journal of Cancer Research and Clinical Oncology·Wasaburo KoizumiUNKNOWN JACCRO and KCSG Study Group
May 31, 2014·World Journal of Gastroenterology : WJG·Özgür AkgülMesut Tez

❮ Previous
Next ❯

Methods Mentioned

BETA
surgical resection

Related Concepts

Related Feeds

Anorexia Nervosa

Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. Here is the latest research on AN.

Related Papers

Chinese Journal of Cancer Research = Chung-kuo Yen Cheng Yen Chiu
Ping Dong
Revista de gastroenterología del Perú : órgano oficial de la Sociedad de Gastroenterología del Perú
Francisco BerrospiFrank Young
© 2021 Meta ULC. All rights reserved