Long-term transcutaneous monitoring of oxygen tension and carbon dioxide at 42 degrees C in critically ill neonates: improved performance of the tcpo2 monitor with topical metabolic inhibition

European Journal of Pediatrics
S FanconiL Molinari

Abstract

Whereas during the last few years handling of the transcutaneous PO2 (tcPO2) and PCO2 (tcPCO2) sensor has been simplified, the high electrode temperature and the short application time remain major drawbacks. In order to determine whether the application of a topical metabolic inhibitor allows reliable measurement at a sensor temperature of 42 degrees C for a period of up to 12 h, we performed a prospective, open, nonrandomized study in a sequential sample of 20 critically ill neonates. A total of 120 comparisons (six repeated measurements per patient) between arterial and transcutaneous values were obtained. Transcutaneous values were measured with a control sensor at 44 degrees C (conventional contact medium, average application time 3 h) and a test sensor at 42 degrees C (Eugenol solution, average application time 8 h). Comparison of tcPO2 and PaO2 at 42 degrees C (Eugenol solution) showed a mean difference of +0.16 kPa (range +1.60 to -2.00 kPa), limits of agreement +1.88 and -1.56 kPa. Comparison of tcPO2 and PaO2 at 44 degrees C (control sensor) revealed a mean difference of +0.02 kPa (range +2.60 to -1.90 kPa), limits of agreement +2.12 and -2.08 kPa. Comparison of tcPCO2 and PaCO2 at 42 degrees C (Eugenol solution) show...Continue Reading

References

Jan 1, 1979·Archives of Oral Biology·J M CotmoreI M Shapiro
Mar 1, 1988·The Journal of Pediatrics·S Fanconi
Mar 1, 1983·The Journal of Pediatrics·V A Harpin, N Rutter
May 1, 1994·Journal of Dental Research·J H JengM Y Kuo

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Citations

Jul 8, 2011·Scandinavian Journal of Clinical and Laboratory Investigation·Line C SørensenGorm Greisen
Jan 30, 2015·Journal of Rehabilitation Research and Development·Gary A Wu, Kath M Bogie

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