Long-term treatment of ADHD with stimulants: a large observational study of real-life patients

Journal of Attention Disorders
Shelagh G PowellHelle Rasmussen

Abstract

To evaluate 410 real-life patients treated with stimulants and assessed systematically over several years. Naturalistic observational study. A database was compiled on the basis of a review of the medical charts of patients attending a specialized ADHD clinic. The diversity of ADHD patients was evident from the comorbidity, age at start, comedication, and treatment needs over time. Dosages corresponded to guidelines in most patients, but some needed higher dosages or got along on lower dosages for long periods. Age at start and comorbidity influenced dosage, and dosage was associated to differential outcome groups. The study findings underscored the diversity of ADHD patients and that individual factors should be taken into account when tailoring individual treatment schedules. Findings further showed that stimulant dosages are dynamic over time and depend on individual factors, that individual factors influence outcome, and that patients with ADHD should be individually monitored and stimulant dosages adjusted continuously.

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Citations

Sep 26, 2015·Basic & Clinical Pharmacology & Toxicology·Mats Fredriksen, Dawn E Peleikis
Nov 19, 2015·Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række·Hanne Cecilie Kaspersen, Berit Hjelde Hansen
Dec 3, 2014·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Mats FredriksenDawn E Peleikis
Oct 31, 2015·Child and Adolescent Psychiatry and Mental Health·Shelagh Gwendolyn PowellPer Hove Thomsen
Jan 24, 2013·Research in Developmental Disabilities·Yueh-Ming TaiChurn-Shiouh Gau
Aug 25, 2012·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Mats FredriksenJan Haavik
Apr 1, 2014·Journal of Attention Disorders·Michael B LensingStein Opjordsmoen

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