PMID: 8945491Dec 1, 1996Paper

Long-term treatment of C1 inhibitor deficiency with epsilon-aminocaproic acid in two patients

Mayo Clinic Proceedings
R G Van Dellen

Abstract

Most patients who have hereditary angioedema receive treatment with androgens or impeded androgens. epsilon-Aminocaproic acid (EACA) is another treatment for C1 inhibitor deficiency. In two patients with angioedema and attacks of abdominal pain due to C1 inhibitor deficiency, long-term treatment with EACA (for more than 2 decades in one of them) was associated with a substantial decrease in the frequency and severity of episodes. One patient had definite hereditary angioedema, and the other had probable hereditary angioedema but the family history was negative for the disease. The EACA therapy caused no major side effects.

Citations

Feb 26, 2005·Clinical and Experimental Immunology·M M GompelsD Watters
Apr 27, 2010·Anesthesia and Analgesia·Jerrold H LevyJohn Roback
Aug 26, 1998·Anesthesia and Analgesia·N F Jensen, J M Weiler
Oct 24, 2003·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Bruce C Ritchie
Jul 14, 2006·Mayo Clinic Proceedings·Catherine R Weiler, Richard G van Dellen

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