Long-term treatment of Hashimoto's encephalopathy

The Journal of Neuropsychiatry and Clinical Neurosciences
Gad A Marshall, John J Doyle

Abstract

Hashimoto's encephalopathy (HE) has been described as an encephalopathy, with acute or subacute onset, accompanied by seizures, tremor, myoclonus, ataxia, psychosis, and stroke-like episodes, with a relapsing/remitting or progressive course. HE patients have positive antithyroid antibodies, are usually in a subclinical hypothyroid state, have elevated cerebral spinal fluid (CSF) protein, and have nonspecific electroencephalogram (EEG) and imaging abnormalities in the absence of CNS infection, tumor, or stroke. The authors present two cases of HE, demonstrating an excellent response to high dose steroids acutely followed by long-term treatment with steroids and other immunomodulatory agents. A review of the literature is also provided.

Citations

Mar 28, 2013·Neurocritical Care·B ChaigneD Perrotin
Jan 1, 2011·BMJ Case Reports·Bodiabaduge A P JayasekeraGeetha Anand
Dec 22, 2007·Clinical Practice and Epidemiology in Mental Health : CP & EMH·Alberto BocchettaMario Piga
Jan 1, 2012·Journal of Community Hospital Internal Medicine Perspectives·Natallia MarozRobert Dobbin Chow
Apr 5, 2012·Korean journal of pediatrics·Min-Joo LeeDa-Eun Jung
Nov 27, 2008·Bipolar Disorders·Masanori NagamineSoichiro Nomura
Aug 26, 2009·Movement Disorders : Official Journal of the Movement Disorder Society·Flávio Sekeff SallemEgberto Barbosa
Oct 14, 2009·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·Sara MekuriaBrian J Harte
Dec 1, 2012·Rinshō shinkeigaku = Clinical neurology·Makoto Yoneda
Jun 30, 2009·American Journal of Alzheimer's Disease and Other Dementias·Gediminas Gliebus, Carol F Lippa
Aug 15, 2014·Journal of Clinical Apheresis·Melissa K CookMatthew S Karafin
Jun 22, 2016·Acta Neurologica Scandinavica·J Y ZhouL Li
Aug 30, 2017·Geriatrics & Gerontology International·Daisuke HiroseHaruo Hanyu
Nov 28, 2017·Current Treatment Options in Neurology·Malcolm Proudfoot, Alastair Wilkins
Jul 18, 2019·Acta neurologica Belgica·Muhammet Gultekin KutlukSerap Teber
Aug 8, 2019·The Cerebellum·Tommaso ErcoliAntonella Muroni
May 28, 2019·Frontiers in Neurology·Jie Li, Fengzhen Li
Jul 17, 2014·Current Neurology and Neuroscience Reports·Howard S Kirshner
Jun 14, 2017·Case Reports in Medicine·Murugan Selvaraj KarthikRamasamy Balakrishnan
Jun 5, 2018·Rinshō shinkeigaku = Clinical neurology·Kinya MatsuoTakashi Kanda
May 8, 2018·Endocrinology, Diabetes & Metabolism Case Reports·Kate LaycockNemanja Stojanovic
Feb 27, 2020·Rinshō shinkeigaku = Clinical neurology·Shizuka HaradaToshiro Yonehara
Sep 14, 2007·CNS Drugs·Ramon MocellinDennis Velakoulis
Sep 2, 2009·Arquivos de neuro-psiquiatria·Renata Telles Rudge de Aquino, Eduardo Genaro Mutarelli
Mar 1, 2012·Expert Review of Endocrinology & Metabolism·Regina PrombergerJohannes Ott
Jan 5, 2010·Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie·Renate Voll
Apr 16, 2019·Internal Medicine·Masahiro NaganoRyosuke Takahashi
Feb 14, 2015·BMJ Case Reports·Arjun GuptaAmbarish Pandey
Feb 13, 2016·International Journal of Bipolar Disorders·Alberto BocchettaAndrea Loviselli
Dec 22, 2020·CNS Neuroscience & Therapeutics·Zhenwei GuoMingli He
Jan 8, 2021·Curēus·Aleksandra SliwinskaJennifer Baldwin
Oct 17, 2020·Journal of Clinical Apheresis·Tina S IpeJay S Raval
Apr 15, 2021·AACE Clinical Case Reports·Anne-Marie D Kaulfers, Samar K Bhowmick
Jun 1, 2021·Case Reports in Neurological Medicine·Naman ZalaTimolaos Rizos
Nov 13, 2021·The Journal of Neuropsychiatry and Clinical Neurosciences·Scott M McGinnisKirk R Daffner

❮ Previous
Next ❯

Related Concepts

Related Feeds

Ataxias (MDS)

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on ataxia here.

Ataxia

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on ataxia here.

Ataxias

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on different types of ataxias here.

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

Autoimmune Thyroiditis

Autoimmune thyroiditis is an inflammatory disease of thyroid gland due to autoimmune responses leading to lymphocytic infiltration of the gland. It is characterized by the presence of circulating thyroid antigen-specific T-cells and thyroid autoantibodies. Discover the latest research on autoimmune thyroiditis here.