LONG-TERM VISUAL OUTCOMES AND CLINICAL FEATURES AFTER ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR INJECTION-RELATED ENDOPHTHALMITIS

Retina
Nadim RayessJason Hsu

Abstract

To determine long-term visual outcomes in patients who developed endophthalmitis after intravitreal anti-vascular endothelial growth factor injections and to correlate visual outcomes with clinical features. This is a retrospective, multicenter, consecutive case series of patients diagnosed with anti-vascular endothelial growth factor injection-related endophthalmitis who were treated at Mid Atlantic Retina, the Retina Service of Wills Eye Hospital, Philadelphia, PA, and the University of Southern California Roski Eye Institute, Los Angeles, CA. Patients were included if they had at least 1 year of follow-up. Primary outcome was to evaluate long-term visual outcomes up to 5 years of follow-up. The secondary outcome was to determine clinical features (e.g., culture results) that may predict long-term visual acuity outcomes. A total of 56 cases of endophthalmitis from 168,247 anti-vascular endothelial growth factor injections were identified (0.033%, 1/3,004 injections), from which 51 eyes met inclusion criteria. Mean follow-up period was 3.3 years (median 4 years; range 1-5 years). A total of 24 patients (47%) reached a maximum final follow-up of 5 years. Mean Snellen visual acuity at the causative injection visit was 20/102 and...Continue Reading

References

Oct 6, 2006·The New England Journal of Medicine·Philip J RosenfeldUNKNOWN MARINA Study Group
Jun 3, 2009·Ophthalmology·Kathryn S KleinJonathan L Prenner
Jun 19, 2010·Retina·Ninel Z GregoriPhilip J Rosenfeld
Jun 28, 2011·Ophthalmology·Chirag P ShahUNKNOWN Post-Injection Endophthalmitis (PIE) Study Team
Jan 24, 2012·American Journal of Ophthalmology·Roger A GoldbergSerafin Gonzalez
Mar 19, 2014·Ophthalmic Surgery, Lasers & Imaging Retina·John B FiletaHarry W Flynn
Jul 17, 2014·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·A GuptaI C J W Bowler
Jan 21, 2015·Ophthalmology·Travis A MeredithUNKNOWN Comparison of Age-Related Macular Degeneration Treatments Trials Research Group
May 6, 2015·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Philip StoreyUNKNOWN Post-Injection Endophthalmitis Study Team
Aug 14, 2015·JAMA Ophthalmology·Brian L VanderBeekLiyuan Ma
Nov 21, 2015·The British Journal of Ophthalmology·Nadim RayessJason Hsu
Jan 14, 2016·Journal of Ophthalmic Inflammation and Infection·Mira M SachdevaAdrienne W Scott

❮ Previous
Next ❯

Citations

Sep 6, 2020·American Journal of Ophthalmology·Samir N PatelUNKNOWN Wills Post-Injection Endophthalmitis (PIE) Study Group
Jun 30, 2021·Ophthalmic Surgery, Lasers & Imaging Retina·Dilsher S DhootNamrata Saroj
Jun 30, 2021·Ophthalmic Surgery, Lasers & Imaging Retina·Daniela P Reyes-CapoUNKNOWN Endophthalmitis/Anti-VEGF Study Group*
Jul 27, 2021·Ophthalmic Surgery, Lasers & Imaging Retina·Samir N PatelSunir J Garg

❮ Previous
Next ❯

Related Concepts

Related Feeds

Arterial-Venous in Development & Disease

Arterial-venous development may play a crucial role in cardiovascular diseases. Here is the latest research.