Long-term visual outcomes of penetrating keratoplasty for Peters anomaly

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Ji Woong ChangYoung Suk Yu

Abstract

To investigate the long-term results and visual outcomes of penetrating keratoplasty (PKP) in Peters anomaly. Twenty-three eyes from 22 patients with Peters anomaly who underwent PKP from 1998 to 2008 were reviewed retrospectively. Patients who were followed for more than 3 years after the first PKP were included in this study. The systemic and ophthalmic features of the recipients were assessed, and the various prognostic factors for graft survival were evaluated. Disease severity was determined according to other accompanying eye anomalies in mild or severe form. The final visual outcomes were presented with respect to graft clarity. Among the 22 patients, 14 patients had unilateral disease, and eight patients had bilateral disease. Associated systemic anomalies were observed in six patients. The mean age at the first PKP was 42.4 months. Nineteen eyes (83 %) underwent PKP after 12 months of age. The graft failure rates at 1 year, 3 years, 5 years, and 10 years after PKP were 30 %, 39 %, 70 %, and 77 % respectively. Graft rejection within 1 month after PKP and severe disease were significant risk factors for graft failure. The mean final VAs in the clear-graft group and the failed-graft group were 1.883 logMAR and 2.767 logMA...Continue Reading

References

Jul 1, 1975·Survey of Ophthalmology·G O WaringP R Laibson
Feb 1, 1976·American Journal of Ophthalmology·D L StoneS J Ryan
Mar 1, 1990·Ophthalmology·J W Cowden
Oct 1, 1971·American Journal of Ophthalmology·I Nakanishi, S I Brown
Mar 1, 1966·Archives of Ophthalmology·A B Reese, R M Ellsworth
Oct 1, 1984·Ophthalmology·R Doyle StultingJ A Gammon
Apr 4, 2000·Cornea·M K AasuriS Gupta
Mar 19, 2005·The British Journal of Ophthalmology·H Y PatelC N J McGhee
Mar 1, 2006·Investigative Ophthalmology & Visual Science·Kilian Schulze-BonselMichael Bach
Jul 4, 2006·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Dany M NajjarC Gail Summers
Jul 3, 2007·American Journal of Ophthalmology·Gerald W ZaidmanCatherine C Furey
Jul 25, 2008·Cornea·Kavita V RaoVirender S Sangwan
Apr 28, 2009·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Lucy L H YangR Doyle Stulting
Sep 3, 2009·Cornea·Charles HuangMark J Mannis

Citations

Feb 17, 2017·Cornea·Haruna YoshikawaShigeru Kinoshita
May 10, 2017·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·S ReichlT Reinhard
Sep 24, 2016·The British Journal of Ophthalmology·Jia-xu HongJian-jiang Xu
May 1, 2018·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Oriel SpiererTa Chen Chang
Jun 1, 2014·International Ophthalmology Clinics·Erin D Stahl
Mar 17, 2020·Journal of Pediatric Ophthalmology and Strabismus·Huda SheheitliAlana L Grajewski
Oct 15, 2014·The American Orthoptic Journal·Anagha MedsingeKen K Nischal
Jul 1, 2017·BMC Ophthalmology·Rui-Qi ChangYi Lu

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Nodding Syndrome

Nodding Syndrome is a neurological and epileptiform disorder characterized by psychomotor, mental, and growth retardation. Discover the latest research on Nodding Syndrome here.

LRRK2 & Microtubules

Mutations in the LRRK2 gene are risk-factors for developing Parkinson’s disease (PD). LRRK2 mutations in PD have been shown to enhance its association with microtubules. Here is the latest research.