Long-term voluntary ethanol drinking increases expression of NMDA receptor 2B subunits in rat frontal cortex

European Journal of Pharmacology
Markus S H HennigerS M Hölter

Abstract

Forced ethanol drinking for several days and application of ethanol to cell cultures changes expression levels of various NMDA receptor subunits in rodents. Therefore, we investigated the influence of long-term voluntary ethanol consumption on the expression of NMDA receptor 2B (NR2B) subunits in several forebrain regions of rats [corrected]. This result is in accordance with and extends findings from studies using high doses of ethanol for a short period and suggests that the NR2B might be a potential target for an effective treatment of alcoholic patients.

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Citations

Sep 10, 2011·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Myoung-Sun RohUng Gu Kang
Jul 24, 2004·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Dorit Ron
Aug 21, 2014·Addiction Biology·Stéphanie Alaux-CantinMickaël Naassila
Aug 21, 2007·Biochemical Pharmacology·Justin T Gass, M Foster Olive
Aug 1, 2006·Progress in Neuro-psychopharmacology & Biological Psychiatry·Chris PickeringHelgi B Schiöth
May 20, 2015·Theoretical Biology & Medical Modelling·Carlos A Gutierrez, Mary M Staehle
Aug 5, 2011·Epigenetics : Official Journal of the DNA Methylation Society·Mei QiangJi Li
Jun 17, 2018·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Oliver VranjkovicDanny G Winder
Nov 2, 2019·Neuroscience and Biobehavioral Reviews·Roberto U CofresíThomas M Piasecki

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