Long working hours and cardiovascular disease: a meta-analysis of epidemiologic studies

Journal of Occupational and Environmental Medicine
Mo-Yeol KangYun-Chul Hong

Abstract

To conduct a meta-analysis from published studies to evaluate the relationship between long working hours and the risk of cardiovascular disease (CVD). Among a total of 341 published studies found from publicly accessible databases, five cohort studies and six case-control studies were analyzed for the study. Statistically significant heterogeneity has been observed (P = 0.037). The effect of longer working hours was significantly associated with the risk of CVD in the random-effects model of all 11 studies (odds ratio, 1.37; 95% confidence interval, 1.11 to 1.70). On the basis of meta-regression analysis, the result was not affected by the mean age, region, or the study year. The P value using Eager test was 0.701 suggesting this analysis was unlikely to have any publication bias. These findings provide evidence of increased CVD with long working hours.

References

Mar 1, 1992·Human & Experimental Toxicology·H N SaiyedS K Kashyap
Dec 1, 1992·Journal of Psychosomatic Research·P R Falger, E G Schouten
Jul 1, 1992·Journal of Psychosomatic Research·R van Diest, A Appels
Feb 1, 1992·Archives of Internal Medicine·K Rost, G R Smith
Apr 1, 1990·The British Journal of Psychiatry : the Journal of Mental Science·A Appels
Jan 1, 1973·Journal of Psychosomatic Research·H G ThielT A Bruce
Jan 1, 1983·Archives of Environmental Health·R D Jones, D P Winter
Jan 1, 1983·Sleep·D L Wingard, L F Berkman
Jan 1, 1980·Psychotherapy and Psychosomatics·J Eyer
Mar 1, 1996·American Journal of Public Health·J V JohnsonT Theorell
Jan 1, 1996·Archives of Toxicology·P HoffmannM Toraason
Oct 1, 1996·Journal of Occupational and Environmental Medicine·T HayashiE Yano
Oct 1, 1996·Scandinavian Journal of Work, Environment & Health·S Maruyama, K Morimoto
Aug 30, 1997·Lancet·T KageyamaM Kabuto
Aug 12, 1998·American Journal of Industrial Medicine·A M Trinkoff, C L Storr
Sep 18, 1998·BMJ : British Medical Journal·S Sokejima, S Kagamimori
Mar 13, 1999·American Journal of Hypertension·P LusardiR Fogari
Jul 11, 2002·Occupational and Environmental Medicine·Y LiuUNKNOWN Fukuoka Heart Study Group
May 3, 2003·Industrial Health·Kimio TarumiKanehisa Morimoto
Jul 6, 1964·JAMA : the Journal of the American Medical Association·R H ROSENMANN T WERTHESSEN
Aug 6, 2005·European Journal of Epidemiology·Tim S NawrotHarry A Struijker-Boudier
Mar 24, 2006·Psychosomatic Medicine·Tea LallukkaEero Lahelma
Dec 19, 2006·Scandinavian Journal of Work, Environment & Health·Mika KivimäkiJussi Vahtera
Mar 7, 2007·Circulation·Fernando LanasUNKNOWN INTERHEART Investigators in Latin America
Apr 24, 2007·American Journal of Industrial Medicine·Jong-Dar ChenShu-Tin Hsiao
Jul 15, 2009·Environmental Health : a Global Access Science Source·Laila M E SabikSafwat El-Refaei
May 13, 2010·European Heart Journal·Marianna VirtanenMika Kivimäki
Jul 29, 2010·American Journal of Industrial Medicine·Jungsun ParkYangho Kim
Apr 6, 2011·Annals of Internal Medicine·Mika KivimäkiMartin J Shipley

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Citations

Feb 19, 2016·British Journal of Cancer·Katriina HeikkilaUNKNOWN IPD-Work Consortium
Mar 23, 2013·Psychophysiology·Yu-Hsuan LinCheryl C H Yang
Aug 29, 2014·American Journal of Industrial Medicine·Mo-Yeol KangYun-Chul Hong
Nov 8, 2014·Journal of Occupational and Environmental Medicine·Luenda E CharlesAna V Diez Roux
Nov 21, 2014·Journal of Occupational Health·Tae-Won JangJong-Uk Won
Mar 11, 2015·Journal of Occupational Health·Chang-Gyo YoonJin-Ha Yoon
Mar 8, 2019·Circulation Journal : Official Journal of the Japanese Circulation Society·Rie HayashiUNKNOWN Japan Public Health Center-Based (JPHC) Prospective Study Group
Dec 18, 2019·American Journal of Industrial Medicine·Penelope J AllisonLuenda E Charles
Mar 8, 2016·Journal of Occupational and Environmental Medicine·Sadie H ConwayDavid Gimeno
Feb 14, 2020·International Journal of Environmental Research and Public Health·Jien-Wen ChienYu-Hsuan Lin
Jan 1, 2014·Annals of Occupational and Environmental Medicine·Dong Hyun YooSung-Il Cho
Mar 5, 2019·Work : a Journal of Prevention, Assessment, and Rehabilitation·Umit Guner
Jun 27, 2019·Journal of Occupational Health·Dong-Wook LeeMo-Yeol Kang
Jun 25, 2020·Occupational and Environmental Medicine·Dong-Wook LeeMo-Yeol Kang
Jun 16, 2019·International Journal of Environmental Research and Public Health·Kapo WongS C Ngan
Nov 10, 2020·Work : a Journal of Prevention, Assessment, and Rehabilitation·Umit Guner, Neslihan Guner
Feb 17, 2021·The Canadian Journal of Cardiology·Paul J ConnellyValeria Raparelli

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