Longer Duration Versus Increasing Power During Radiofrequency Ablation Yields Different Ablation Lesion Characteristics

JACC. Clinical Electrophysiology
Ryan T BorneDuy T Nguyen

Abstract

The goal of this study was to characterize differences in ablation lesions with varying radiofrequency ablation (RFA) power and time. Increasing power delivery or prolonging duration can improve the efficacy of RFA. However, the extent to which ablation lesion characteristics change, based on varying degrees of power and duration, is unknown. An ex vivo model consisting of viable bovine myocardium in a circulating warmed saline bath was used. An open irrigated RFA catheter was positioned with 10 g of force in the perpendicular position, and RFA was delivered at powers of 20, 30, 40, and 50 W and for various time intervals, up to a total of 90 s, at each power. An in vivo porcine thigh preparation model was used to perform RFA at 50 W for 5 s and 20 W for 30 s. Lesion volumes were analyzed. Greater power delivery and longer radiofrequency time increased ablation lesion size. However, compared with a proportional change in radiofrequency duration, the same proportional increase in power produced a significantly larger lesion volume (p < 0.01). For in vivo models, 50 W/5 s ablation lesions yielded similar volumes but significantly less depth than 20 W/30 s ablation lesions. Peak temperatures were not significantly different at 2 a...Continue Reading

References

Oct 18, 2006·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Brian NilssonJesper Hastrup Svendsen
Mar 8, 2008·Heart Rhythm : the Official Journal of the Heart Rhythm Society·T Jared Bunch, John D Day
Nov 6, 2009·The American Journal of Gastroenterology·Ulrich HalmDaniela Husser
Jan 7, 2011·Pacing and Clinical Electrophysiology : PACE·Roger A WinkleRob A Patrawala
Sep 12, 2013·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Matthew D OlsonWilliam H Sauer
Aug 6, 2014·Journal of Cardiovascular Electrophysiology·Duy T NguyenWilliam H Sauer
Oct 26, 2016·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Duy T NguyenWilliam H Sauer

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Citations

Jun 6, 2019·Circulation. Arrhythmia and Electrophysiology·William H Sauer, Wendy S Tzou
Oct 31, 2019·Circulation. Arrhythmia and Electrophysiology·Arvindh KanagasundramWilliam G Stevenson
Dec 13, 2019·Journal of Cardiovascular Electrophysiology·Amneet Sandhu, Duy T Nguyen
Jan 29, 2020·Expert Review of Medical Devices·Alessandro RizzoGian-Battista Chierchia
Nov 13, 2019·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Sergio Castrejón-CastrejónJosé Luis Merino
Jul 6, 2020·Journal of Cardiovascular Electrophysiology·Jie QiuGuangzhi Chen
Aug 19, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Dong Geum ShinHong Euy Lim
Apr 24, 2020·Journal of Cardiovascular Electrophysiology·Albert J RogersDuy T Nguyen
Jan 14, 2021·Pacing and Clinical Electrophysiology : PACE·Aditi Naniwadekar, Srinivas R Dukkipati
May 6, 2021·Journal of Cardiovascular Electrophysiology·Shigeki KusaTetsuo Sasano
Jun 18, 2021·Circulation. Arrhythmia and Electrophysiology·Atul VermaMichael K Getman
Dec 19, 2021·Journal of Cardiovascular Electrophysiology·Gavin S ChuDhiraj Gupta
Jan 9, 2022·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Cristina Lozano GraneroJavier Moreno
Jan 21, 2022·Journal of Cardiovascular Electrophysiology·Weeranun Bode, Pasquale Santangeli

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