Longitudinal analysis of the association of human salivary antimicrobial agents with caries increment and cariogenic micro-organisms: a two-year cohort study

Journal of Dental Research
V KirstiläJ Tenovuo

Abstract

Previous studies of the possible associations of salivary antimicrobial agents with dental caries have given controversial results, obviously mainly because almost all studies have been cross-sectional. Our aim was to find out, in a two-year longitudinal follow-up study, the associations among selected salivary non-immune and immune antimicrobial variables, cariogenic bacteria, and caries increment. The study population was comprised of 63 subjects, all of whom had their 13th birthday during the first study year. In addition to a comprehensive dental examination at baseline and after 2 yrs, paraffin-stimulated whole saliva samples were collected in a standardized way at six-month intervals. Saliva samples were analyzed for flow rate, buffer effect, lysozyme, lactoferrin, total peroxidase activity, hypothiocyanite, thiocyanate, agglutination rate, and total and specific anti-S. mutans IgA and IgG, as well as for numbers of total and mutans streptococci, lactobacilli, and total anaerobic bacteria. Cluster analysis and Spearman-Rank correlation coefficients were used to explore possible associations between and among the studied variables. During the two-year period, a statistically significant increase was observed in flow rate, ...Continue Reading

References

Oct 1, 1992·Oral Microbiology and Immunology·M Lenander-Lumikari
Dec 1, 1990·Acta Odontologica Scandinavica·L SaxénP Vilja
Jan 1, 1986·Infection and Immunity·J TenovuoP Tuohimaa
Jun 1, 1988·Oral Microbiology and Immunology·J TenovuoG Sievers
Feb 1, 1987·Journal of Dental Research·D J SmithJ L Ebersole
Feb 1, 1987·Journal of Dental Research·J TenovuoP Vilja
Feb 1, 1987·Journal of Dental Research·B Mansson-RahemtullaF Rahemtulla
Jan 1, 1986·Archives of Oral Biology·B Mansson-RahemtullaF Rahemtulla
Apr 22, 1986·Biochimica Et Biophysica Acta·K M PruittD C Baldone
Jan 21, 1985·Journal of Immunological Methods·P ViljaP Tuohimaa
Jan 1, 1985·Journal of Clinical Immunology·R L GregoryJ R McGhee
Aug 1, 1983·Journal of Dental Research·I D MandelD Weinstein
Jun 1, 1980·Infection and Immunity·R R ArnoldJ J Gauthier
Aug 1, 1980·Infection and Immunity·V J IaconoJ J Pollock
Feb 1, 1995·Oral Microbiology and Immunology·M GuE J Bergey
Jul 1, 1994·Journal of Clinical Immunology·V KirstiläP Vilja
Dec 1, 1993·Archives of Oral Biology·H NikawaT Hamada
Mar 1, 1994·Journal of Dental Research·J van Houte
Jan 1, 1995·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·J D Rudney

❮ Previous
Next ❯

Citations

Sep 16, 2004·Journal of Paediatrics and Child Health·S R LeeY H Choi
Aug 30, 2005·Antimicrobial Agents and Chemotherapy·Renchuan TaoBeverly A Dale
Aug 29, 2006·BMC Oral Health·Beverly A DaleRichard J Jurevic
Jan 1, 2010·Contemporary Clinical Dentistry·Sumati BhallaK Satyamoorthy
Jun 10, 2000·Australian Dental Journal·L B Messer
Dec 15, 2015·Periodontology 2000·Xiaoli GaoChin-Ying Stephen Hsu
Feb 4, 2016·Journal of the Indian Society of Pedodontics and Preventive Dentistry·Sawinderjit SainiP K Shivaprakash
Nov 3, 2009·Periodontology 2000·Sven-Ulrik Gorr
Jun 19, 2002·International Journal of Hygiene and Environmental Health·Juergen HoelzerMichael Wilhelm
Oct 19, 2016·Saudi Pharmaceutical Journal : SPJ : the Official Publication of the Saudi Pharmaceutical Society·Zohaib KhurshidMuhammad Sohail Zafar
Feb 15, 2002·Advances in Dental Research·M Lenander-Lumikari, V Loimaranta
Dec 3, 2016·Experimental Biology and Medicine·Karolina Elżbieta Kaczor-UrbanowiczDavid Tw Wong
May 12, 2017·Brazilian Dental Journal·Priscila Raquel SchirokyFabrício Mezzomo Collares
Apr 27, 2018·The Journal of Clinical Pediatric Dentistry·Eloa Ramalho de CamargoMichelle Darrieux
Nov 6, 2013·Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry·Priya SubramaniamLakshmi Mohan Das
Feb 23, 2020·Journal of Functional Biomaterials·Paola Andrea Mena SilvaFabrício Mezzomo Collares
Dec 22, 2020·Dental Materials : Official Publication of the Academy of Dental Materials·Isadora Martini GarciaMary Anne S Melo
Feb 25, 2015·The Journal of Contemporary Dental Practice·Maryam GhasempourMahtab Hamzeh
May 18, 2018·Open Life Sciences·Galina LaputkováJán Sabo
May 28, 2019·Dental Materials : Official Publication of the Academy of Dental Materials·Isadora Martini GarciaFabrício Mezzomo Collares
Aug 23, 2005·Archives of Biochemistry and Biophysics·Riikka IhalinJorma Tenovuo

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antibodies: Agglutination

Antibody-mediated agglutination is the clumping of cells in the presence of antibody, which binds multiple cells together. This enhances the clearance of pathogens. Find the latest research on antibody-mediated agglutination here.

Bacterial Cell Wall Structure (ASM)

Bacterial cell walls are made of peptidoglycan (also called murein), which is made from polysaccharide chains cross-linked by unusual peptides containing D-amino acids. Here is the latest research on bacterial cell wall structures.

Bacterial Cell Wall Structure

Bacterial cell walls are made of peptidoglycan (also called murein), which is made from polysaccharide chains cross-linked by unusual peptides containing D-amino acids. Here is the latest research on bacterial cell wall structures.