Longitudinal and cross-sectional studies of the relationship between 6-keto PGF1 alpha and high density lipoproteins

Prostaglandins, Leukotrienes, and Essential Fatty Acids
J D Symons

Abstract

Two studies were performed to examine the relationship between Prostacyclin (PGI2) and high density lipoprotein cholesterol (HDL-C). A longitudinal study examined the stable metabolite of PGI2, 6-keto PGF1 alpha, along with HDL-C, and total cholesterol (TC) before (Week 0), during (Week 4), and after (Week 9) an eight week aerobic conditioning program. 6-keto PGF1 alpha was measured by radioimmunoassay using 125I, and HDL-C and TC were spectrophotometrically analysed. Maximal oxygen uptake and resting heart rate data obtained at Week 0 confirmed that the training group (E) was not different from the sedentary group (C). Results obtained at Week 9 indicated that maximal oxygen uptake was higher (p less than 0.05) and resting heart rate lower (p less than 0.05) in the E group, while these variables remained unchanged in group C. Levels of 6-keto PGF1 alpha, HDL-C, and TC did not differ between groups E and C when Week 0 was compared with Week 9. However, within the E group, significantly lower concentrations of 6-keto PGF1 alpha (p less than 0.05) and HDL-C (p less than 0.05) were found at Week 4 compared with Week 0. A cross-sectional study involving 52 subjects examined the relationship between 6-keto PGF1 alpha and several car...Continue Reading

References

Nov 1, 1976·Metabolism: Clinical and Experimental·P D WoodJ W Farquhar
Apr 1, 1986·Prostaglandins, Leukotrienes, and Medicine·J L Nadler, J V Yamamoto
May 1, 1986·Prostaglandins, Leukotrienes, and Medicine·C GiesslerW Förster
Feb 12, 1983·Lancet·J M RitterC T Dollery
Jun 1, 1984·Medicine and Science in Sports and Exercise·L ViinikkaO Ylikorkala
Apr 1, 1983·Prostaglandins, Leukotrienes, and Medicine·J BeitzW Förster
Apr 1, 1981·Prostaglandins and Medicine·L M DemersR J Santen
Jan 1, 1981·Pharmacological Research Communications·J SwiesR J Gryglewski
Feb 8, 1980·JAMA : the Journal of the American Medical Association·M M Adner, W P Castelli
Jul 1, 1980·The American Journal of Clinical Nutrition·A P GoldbergH R Harter

❮ Previous
Next ❯

Citations

Mar 8, 2011·Current Atherosclerosis Reports·John A Farmer, Joshua Liao
Aug 11, 2006·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Apostolos Thomas Stergioulas, Dimitrios Konstantinos Filippou
Jun 4, 2014·Cardiovascular Research·Marco van der StoepMiranda Van Eck
Mar 27, 2010·Clinical and Experimental Pharmacology & Physiology·Jerzy-Roch NoferBeate E Kehrel
Jun 10, 2006·Circulation Research·Chieko MineoPhilip W Shaul
Sep 13, 2003·Arteriosclerosis, Thrombosis, and Vascular Biology·Laura CalabresiGuido Franceschini
Jun 14, 2019·Arteriosclerosis, Thrombosis, and Vascular Biology·Andrei C SpositoAlan T Remaley
Feb 4, 2010·Current Opinion in Endocrinology, Diabetes, and Obesity·Charles J Lowenstein, Scott J Cameron

❮ Previous
Next ❯

Related Concepts

Related Feeds

ApoE, Lipids & Cholesterol

Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.