Longitudinal computational fluid dynamics study of aneurysmal dilatation in a chronic DeBakey type III aortic dissection

Journal of Vascular Surgery
Christof KarmonikHendrik von Tengg-Kobligk

Abstract

Computational fluid dynamics, which uses numeric methods and algorithms for the simulation of blood flow by solving the Navier-Stokes equations on computational meshes, is enhancing the understanding of disease progression in type III aortic dissections. To illustrate this, we examined the changes in patient-derived geometries of aortic dissections, which showed progressive false lumen aneurysmal dilatation (26% diameter increase) during follow-up. Total pressure was decreased by 29% during systole and by 34% during retrograde flow. At the site of the highest false lumen dilatation, the temporal average of total pressure decreased from 45 to 22 Pa, and maximal average wall shear stress decreased from 0.9 to 0.4 Pa. These first results in the study of disease progression of type III DeBakey aortic dissection with computational fluid dynamics are encouraging.

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Citations

Feb 15, 2013·Interactive Cardiovascular and Thoracic Surgery·Laurant HeimMichael Poullis
Feb 29, 2016·International Journal of Cardiology·Zhonghua Sun, Thanapong Chaichana
Jun 16, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Christof KarmonikAlan B Lumsden
Aug 2, 2014·Journal of Cardiac Surgery·Jake J LeeSalvatore Pasta
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Dec 15, 2015·Frontiers in Cardiovascular Medicine·Andrew G SherrahRajesh Puranik
Oct 26, 2013·Computer Methods in Biomechanics and Biomedical Engineering·Eduardo SoudahEugenio Oñate
Sep 21, 2013·Vascular and Endovascular Surgery·Christof KarmonikHendrik von Tengg-Kobligk
Sep 18, 2013·Vascular·Laura Capoccia, Vicente Riambau
Aug 11, 2018·American Journal of Physiology. Heart and Circulatory Physiology·Farhad Rikhtegar NezamiElazer R Edelman
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Dec 14, 2019·Journal of Vascular Surgery·Bijit MunshiBarry J Doyle

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