Longitudinal evaluation of health-related quality of life after osteoradionecrosis of the mandible

The British Journal of Oral & Maxillofacial Surgery
Simon N RogersAnastasios Kanatas

Abstract

There is a lack of longitudinal data on the effect of osteoradionecrosis (ORN) on health-related quality of life (HRQoL). We report data on HRQoL across groups of patients with ORN at different stages of disease and reconstruction. We identified 71 patients treated for ORN of the mandible, and cross-referenced the data with their medical records. They were divided into 4 groups according to the Notani classification and patients who did not have ORN were used for comparison. Patients with ORN reported the most pain, and rates were relatively high for problems concerning appearance, activity, recreation, swallowing, and chewing. There were significant differences for pain, appearance, swallowing, and chewing between patients who had ORN and those who did not and had not had radiotherapy. On the University of Washington quality of life questionnaire (UWQoL), patients with ORN reported similar levels of morbidity to those who had had radiotherapy but did not have ORN, particularly on the physical and social-emotional subscales. Those with grade III ORN were particularly affected, and the UWQoL scores after mandibular resection and reconstruction were disappointing. HRQoL after composite resection for Notani grade III disease is re...Continue Reading

References

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Citations

May 5, 2018·Current Opinion in Otolaryngology & Head and Neck Surgery·Blake S Raggio, Ryan Winters
Jan 29, 2019·The Annals of Otology, Rhinology, and Laryngology·Blake S Raggio, Ryan D Winters
Jan 23, 2016·HNO·G SchnurbeinR O Seidl
Feb 24, 2021·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Larissa SweenyMark K Wax
Apr 11, 2021·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·F DutheilM Lapeyre
Jul 31, 2021·The British Journal of Oral & Maxillofacial Surgery·C Y ChiengS N Rogers
Sep 22, 2021·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Mohamed ShamaPeter T Dziegielewski

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