PMID: 16522912Mar 9, 2006Paper

Longitudinal examination of 24-h urinary iodine excretion in schoolchildren as a sensitive, hydration status-independent research tool for studying iodine status

The American Journal of Clinical Nutrition
Thomas RemerShoma Berkemeyer

Abstract

Because worldwide iodine status (IS) depends on continuous fortification, the adequacy of IS needs to be regularly monitored. Our study aimed to evaluate IS in a longitudinal sample of healthy schoolchildren who regularly used table salt iodized with 20 microg I/g. Urine osmolality (Uosm) and 24-h urinary excretion rates of iodine (24-h UI), sodium, creatinine, and total urine volume (24-h Uvol) were measured in 1046 specimens that were collected at repeated intervals from 1996 to 2003 in a sample of 358 German children aged 6-12 y. Energy intake and food consumption were calculated from 3-d weighed dietary records that were collected in parallel to the urine samples. During the 4-y period from 1996 to 1999, the median 24-h UI increased from 87 to 93 microg I/d (P = 0.017), whereas urinary iodine concentration (UIC), Uosm, and 24-h Uvol did not change significantly. Thereafter (from 2000 to 2003), UIC stagnated and Uosm decreased (P = 0.004), whereas 24-h Uvol (P = 0.008) and 24-h UI (P = 0.002) increased. The final median 24-h UI reached 120 microg I/d. Milk, fish, egg, and meat intakes and 24-h sodium excretion were all significant predictors of IS, with an almost doubled contribution from milk intake during the second 4-y pe...Continue Reading

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Citations

Nov 19, 2008·Thyroid : Official Journal of the American Thyroid Association·Kathleen L CaldwellRobert L Jones
Aug 19, 2010·European Journal of Clinical Nutrition·S A JohnerT Remer
Oct 12, 2011·Annals of Nutrition & Metabolism·Till IttermannHenry Völzke
Oct 25, 2011·The British Journal of Nutrition·Omar Dary
Jul 31, 2014·Public Health Nutrition·Elena Rodríguez-RodríguezLiliana G González-Rodríguez
Apr 9, 2009·International Journal of Epidemiology·Ian J BrownPaul Elliott
Oct 2, 2009·The American Journal of Clinical Nutrition·Lijie ShiThomas Remer
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Dec 6, 2012·European Journal of Nutrition·Simone A JohnerThomas Remer
Feb 20, 2014·Thyroid : Official Journal of the American Thyroid Association·Simone A JohnerThomas Remer
Sep 24, 2008·Journal of the American Geriatrics Society·Shoma BerkemeyerThomas Remer
Jun 11, 2015·The British Journal of Nutrition·Gabriela Montenegro-BethancourtThomas Remer
Oct 3, 2014·The British Journal of Nutrition·Sarah C BathMargaret P Rayman
Nov 3, 2010·Thyroid : Official Journal of the American Thyroid Association·Simone A JohnerThomas Remer
Jul 20, 2007·American Journal of Physiology. Endocrinology and Metabolism·Stefan A WudyThomas Remer
Mar 18, 2015·Thyroid : Official Journal of the American Thyroid Association·Gabriela Montenegro-BethancourtThomas Remer
Apr 29, 2018·Annals of Clinical Biochemistry·Patrick Wainwright, Paul Cook
Jul 28, 2020·Biological Trace Element Research·Bassem Refaat, Firas Azzeh
Sep 13, 2008·Clinical Endocrinology·Caterina MianMaria Elisa Girelli
Feb 5, 2016·European Journal of Nutrition·Carla El MallahOmar Obeid
May 8, 2021·Environmental Geochemistry and Health·Saeed AhmadScott D Young

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