Longitudinal Impact of Depression on Quality of Life in Stroke Patients

Psychiatry Investigation
Eun-Song KimJae-Min Kim

Abstract

Stroke is associated with significant long-term morbidity and poor quality of life (QOL). Depression is one of the most common complications after stroke and has been associated with QOL cross-sectionally. We investigated the longitudinal impact of depression in the acute phase of stroke on QOL 1 year after stroke. In total, 423 patients were evaluated 2 weeks after stroke, and 288 (68%) were followed 1 year later. QOL was assessed using the World Health Organization Quality of Life-Abbreviated form (WHOQOL-BREF) at baseline and follow-up. Depression was diagnosed according to Diagnostic and Statistical Manual of Mental Disorders-IV criteria; demographic and clinical characteristics data, including stroke severity, were obtained at baseline. The longitudinal associations of post-stroke depression (PSD) at baseline with QOL across two evaluation points were assessed using a repeated-measures analysis of variance. The WHOQOL-BREF scores were significantly and persistently lower 1 year after stroke in patients with PSD at baseline compared with those without PSD at baseline independent of demographic and clinical characteristics, including stroke severity. PSD in the acute phase of stroke is an independent predictor of QOL in both...Continue Reading

References

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Citations

Aug 20, 2020·Science Progress·Abdulrahman M Alshahrani
Dec 13, 2018·Progress in Rehabilitation Medicine·Hideki AraiTatsuyuki Fukuoka
Sep 30, 2020·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Michael W WilliamsCatherine C Hay
Jul 1, 2021·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Naomi A MaymanLaura K Stein
Jul 7, 2021·International Journal of Geriatric Psychiatry·Eun-Hye LeeJae-Min Kim

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