Longitudinal mapping of cortical thickness and brain growth in normal children

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Elizabeth R SowellArthur W Toga

Abstract

Recent advances in magnetic resonance imaging (MRI) technology now allow the tracing of developmental changes in the brains of children. We applied computer-matching algorithms and new techniques for measuring cortical thickness (in millimeters) to the structural MRI images of 45 children scanned twice (2 yr apart) between the ages 5 and 11. Changes in brain size were also assessed, showing local brain growth progressing at a rate of approximately 0.4-1.5 mm per year, most prominently in frontal and occipital regions. Estimated cortical thickness ranged from 1.5 mm in occipital regions to 5.5 mm in dorsomedial frontal cortex. Gray matter thinning coupled with cortical expansion was highly significant in right frontal and bilateral parieto-occipital regions. Significant thickening was restricted to left inferior frontal (Broca's area) and bilateral posterior perisylvian (Wernicke's area on the left) regions. In the left hemisphere, gray matter thickness was correlated with changing cognitive abilities. For the first time, developmental changes in gray matter thickness, brain size, and structure-function relationships have been traced within the same individuals studied longitudinally during a time of rapid cognitive development.

Citations

May 6, 2009·Archives of General Psychiatry·Aaron L GoldmanAndreas Meyer-Lindenberg
May 4, 2011·Archives of General Psychiatry·Heather Cody HazlettJoseph Piven
Sep 29, 2011·Psychopharmacology·Lindsay M SquegliaSusan F Tapert
Aug 10, 2006·Experimental Brain Research·Donald WatanabeVirginia B Penhune
Apr 14, 2009·Experimental Brain Research·Tal Savion-LemieuxVirginia B Penhune
Dec 15, 2012·Experimental Brain Research·Yu-Kai ChangTsung-Min Hung
Jan 5, 2013·Pediatric Radiology·Lana VasungPetra S Hüppi
Mar 3, 2009·Journal of Neurology·Giovanni B FrisoniPaul M Thompson
Jun 28, 2011·Psychological Research·Angela D FriedericiJens Brauer
Jun 14, 2013·Documenta Ophthalmologica. Advances in Ophthalmology·Vann ChauSteven P Miller
Oct 27, 2010·Neuropsychology Review·Alecia C VogelBradley L Schlaggar
Nov 3, 2010·Neuropsychology Review·Joan Stiles, Terry L Jernigan
Jul 28, 2012·Neuropsychology Review·Jan P PiekMelissa K Licari
Sep 26, 2012·Neuropsychology Review·Timothy T Brown, Terry L Jernigan
Oct 31, 2012·Neuropsychology Review·Peter J Anderson, Natalie Reidy
May 24, 2011·Reviews in Endocrine & Metabolic Disorders·Julie A Markham
Mar 2, 2012·Cognitive Neurodynamics·Vera NenadovicJose Luis Perez Velazquez
Feb 18, 2010·Brain Imaging and Behavior·Tracey A KnausHelen Tager-Flusberg
Mar 21, 2013·Brain Imaging and Behavior·Joana F CoutinhoOscar F Gonçalves
Apr 9, 2013·Cognition·Nicolas ChevalierKimberly Andrews Espy
Oct 6, 2009·Lancet Neurology·Laura R MentPetra S Hüppi
Oct 27, 2006·Development and Psychopathology·Daniel P Dickstein, Ellen Leibenluft
Oct 8, 2008·Development and Psychopathology·Eveline A CroneP D Zelazo
Oct 8, 2008·Development and Psychopathology·Tiago V MaiaBradley S Peterson
Dec 18, 2013·Development and Psychopathology·Monica Luciana
Jun 7, 2013·CNS Spectrums·Idaiane Batista Assunção LemeAndrea Parolin Jackowski
Aug 19, 2007·Journal of the International Neuropsychological Society : JINS·Krista Lisdahl MedinaSusan F Tapert
Jul 6, 2010·Journal of the International Neuropsychological Society : JINS·G Sánchez-BenavidesJ Peña-Casanova
May 23, 2012·Journal of the International Neuropsychological Society : JINS·Krista M Lisdahl, Jenessa S Price
Aug 21, 2013·Journal of the International Neuropsychological Society : JINS·Lindsay M SquegliaSusan F Tapert
Dec 23, 2009·Psychology of Addictive Behaviors : Journal of the Society of Psychologists in Addictive Behaviors·Lindsay M SquegliaSusan F Tapert
Mar 30, 2011·Psychology of Addictive Behaviors : Journal of the Society of Psychologists in Addictive Behaviors·Karen L HansonSandra A Brown
Oct 5, 2007·Nature Clinical Practice. Neurology·Laura R Ment, R Todd Constable
May 20, 2008·Nature Neuroscience·Elizabeth R SowellBradley S Peterson
Oct 2, 2009·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Gregory Z Tau, Bradley S Peterson
Mar 21, 2008·Nature Reviews. Neuroscience·Sarah-Jayne Blakemore
Aug 13, 2009·Nature Reviews. Neuroscience·David Badre, Mark D'Esposito
Aug 21, 2012·Nature Reviews. Neuroscience·Eveline A Crone, Ronald E Dahl

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