Longitudinal Quantification of Eye-Movement Impairments after Pontine Hemorrhage

Frontiers in Neurology
Melis SunerN Jeremy Hill

Abstract

We report a case of hypertrophic olivary degeneration due to pontine hemorrhage. A 59-year-old male with untreated hypertension suffered a primary pontine hemorrhage, which caused horizontal eye-movement limitation. Progressive neurological deterioration with involuntary eye and palatal movements began months after hemorrhage. This was accompanied by magnetic resonance imaging evidence of hypertrophic olivary degeneration at 4.5 months. Primary pontine hemorrhage often leads to impairment of eye movements and diplopia. Hypertrophic olivary degeneration can also emerge months after hemorrhage, producing involuntary pendular eye movements. Neither the natural history of voluntary eye movements nor the emergence of involuntary eye movements after pontine hemorrhage has been previously quantified. We used an optokinetic task that enabled measurement of eye movements. It provided real-time feedback on the ability to track continuously and saccade quickly in a pursuit task. The feedback motivated the patient to use the system repeatedly in his home. From 3 months after hemorrhage, the patient used the system for 9 months, allowing us to quantify changes in his eye movements. Horizontal gaze impairments were manifest in our task as li...Continue Reading

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Citations

Nov 20, 2018·Journal of Vision·Scott W J MooneyGlen T Prusky
Jan 4, 2019·Acta neurologica Belgica·Sung Ho Jang, Hyeok Gyu Kwon

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