Longitudinal spread of adaptation in the rods of the frog's retina

The Journal of Physiology
S Hemilä, T Reuter

Abstract

1. The stimulus-response function of the red rods in the retina of the common frog (Rana temporaria) was determined in different adaptational states by measuring aspartate-isolated receptor responses. 2. Flash stimuli, background adaptations and bleaches were delivered through the same optical channel forming an oblique light-beam striking the receptor side of the isolated and flat-mounted retina at an angle of 10 degrees. 3. When the light was blue-green and optimally polarized the absorbance of the receptor layer was about 2, from which follows that 70-80% of the light was absorbed in the distal third of the rod outer segments, i.e. the exposure was local. Homogeneous exposures of the whole rod outer segments were obtained with orange and red lights. 4. Combinations of homogeneous and local stimuli with homogeneous and local adaptations were used to investigate the longitudinal spread of background, intermediate and opsin adaptation, i.e. the sensitivity-reducing effect of a background light, and the transient and permanent sensitivity losses following a bleach isomerizing 3.5-26% (usually 10%) of the rhodopsin in the retina. 5. The results obtained were related to predictions based both on the assumption that the adaptation ...Continue Reading

Citations

Jan 1, 1987·Vision Research·S Hemilä
Aug 24, 1999·The Journal of Physiology·M Gray-KellerP B Detwiler
Aug 26, 1998·The Journal of Physiology·I PerlmanM Alpern
Mar 20, 2015·Frontiers in Molecular Neuroscience·Owen P GrossMarie E Burns
Sep 20, 2011·Vision Research·Tom Reuter
Jan 1, 1985·CRC Critical Reviews in Biochemistry·J I Korenbrot
Dec 1, 1987·Journal of the Optical Society of America. A, Optics and Image Science·A C Aho Orlov OYu
May 1, 1993·Archives of Disease in Childhood·A LucasR M Morley
Jan 12, 2001·Physiological Reviews·G L FainY Koutalos

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