Longitudinal study of Clostridium difficile and antimicrobial susceptibility of Escherichia coli in healthy horses in a community setting

Veterinary Microbiology
A SchosterJ S Weese

Abstract

Point prevalence studies have reported carriage rates of enteric pathogens in healthy horses, but longitudinal data are lacking. Commensal E. coli is an indicator organism to evaluate antimicrobial resistance of enteric bacteria, yet there are limited data for horses. The objectives of this study were to investigate and molecularly characterize isolates of Clostridium difficile, Clostridium perfringens and Salmonella, collected sequentially over a one year period, and to determine the antibiotic susceptibility profile for E. coli. Fecal samples were collected monthly from 25 adult horses for one year. Selective cultures were performed for all above bacteria. C. difficile isolates were characterized via PCR toxin gene profiling and ribotyping. Broth microdilution was performed to assess antimicrobial susceptibility profiles of E. coli. Toxigenic Clostridium difficile was isolated from 15/275 (5.45%) samples from 10/25 (40%) horses. Four horses were positive at multiple sampling times but different ribotypes were found in three. Ribotypes included 078 (n=6), 001 (n=6) and C (n=3). C. perfringens was not isolated, nor was Salmonella. E. coli was isolated from 232/300 (77%) fecal samples. Resistance to ≥ 1 and ≥ 3 antimicrobials wa...Continue Reading

References

May 1, 1997·Australian Veterinary Journal·D G BucknellK Whithear
Feb 7, 2002·Journal of the American Veterinary Medical Association·Kirsten TillotsonM D Salman
Sep 25, 2004·Antimicrobial Agents and Chemotherapy·Yolanda SáenzCarmen Torres
Jan 28, 2005·Journal of Medical Microbiology·Luis G ArroyoJ Scott Weese
May 5, 2006·Veterinary Pathology·M K Keel, J G Songer
Mar 3, 2007·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M Rupnik
Apr 13, 2007·Journal of Clinical Microbiology·Kevin KeelJ Glenn Songer
Sep 24, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Abraham GoorhuisEd J Kuijper
May 2, 2009·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·J Glenn SongerRobert D Glock
Nov 21, 2009·Journal of Veterinary Internal Medicine·E McKenzieS L Marks
Dec 3, 2009·Epidemiology and Infection·J S WeeseJ Rousseau
Dec 17, 2009·Comparative Immunology, Microbiology and Infectious Diseases·Maria Cristina OssiprandiLaura Zerbini
Apr 9, 2010·Annals of Clinical Microbiology and Antimicrobials·Mohamed O AhmedMalcolm Bennett
Aug 17, 2010·Anaerobe·J Scott WeeseRobert Friendship
May 17, 2011·Veterinary Microbiology·Carlos E Medina-TorresHenry R Staempfli

❮ Previous
Next ❯

Citations

Jun 19, 2015·Equine Veterinary Journal·T W MaddoxG L Pinchbeck
Feb 2, 2013·Equine Veterinary Journal·M Bowen
Aug 6, 2013·The Veterinary Journal·José L BlancoMarta E García
Sep 10, 2013·Infectious Disease Clinics of North America·Dallas G Hoover, Alexander Rodriguez-Palacios
Dec 10, 2013·Applied and Environmental Microbiology·Chelsea G HimsworthJ Scott Weese
Jan 7, 2020·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·J Scott Weese
Mar 4, 2021·Journal of Veterinary Internal Medicine·Jeffrey Scott WeeseJoyce Rousseau
Jul 5, 2017·Research in Veterinary Science·José Antonio BessegattoMarcio Carvalho Costa
Aug 13, 2021·Expert Review of Anti-infective Therapy·Chin-Shiang TsaiWen-Chien Ko

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.