Longitudinal study of dental caries incidence associated with Streptococcus mutans and Streptococcus sobrinus in patients with intellectual disabilities

BMC Oral Health
Yuki OdaMitsugi Okada

Abstract

Mutans streptococci (Streptococcus mutans and S. sobrinus) are considered to be major etiologic agents of dental caries. Using a polymerase chain reaction method, we detected those bacteria from 145 outpatients (6-30 years old) with intellectual disabilities (ID) and their presence was compared with the incidence of dental caries. Plaque samples were collected from all erupted tooth sites in subjects with a sterile toothbrush. A dental examination was performed to determine the number of decayed and filled teeth (DFT score) in permanent dentition using the WHO caries diagnostic criteria. A Mann-Whitney U-test was employed to compare the caries scores between combinations of the bacteria, and with a Wilcoxon rank test used to compare caries scores between the baseline and after 1 year. Among all subjects, S. mutans and S. sobrinus were possessed by 78.7 and 83.5%, respectively, while 13.1% were positive for S. mutans alone, 17.9% for S. sobrinus alone, and 65.6% for both organisms, with 3.4% were negative for both. The mean DFT score of subjects positive for both S. mutans and S. sobrinus at after 1 year was significantly higher than that of those positive for S. mutans alone (P < 0.01). The increase in caries increment was also...Continue Reading

References

Nov 1, 1990·Journal of Clinical Microbiology·J J de SoetJ de Graaff
Mar 1, 1989·Oral Microbiology and Immunology·G L SmithC M Smith
Jul 1, 1989·Journal of Dental Research·P D MarshA F Pitter
Dec 1, 1987·Community Dentistry and Oral Epidemiology·B Köhler, S Bjarnason
Apr 1, 1995·Community Dentistry and Oral Epidemiology·B KöhlerW P Holbrook
Oct 1, 1994·Journal of Medical Microbiology·T OnoK Fukui
Oct 1, 1996·Oral Microbiology and Immunology·T IgarashiN Goto
Mar 27, 1999·Oral Microbiology and Immunology·R A Whiley, D Beighton
Dec 29, 2000·Journal of Medical Microbiology·T IgarashiN Goto
Feb 13, 2003·Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry·Kauko K MäkinenEva Söderling
Jan 5, 2006·Oral Microbiology and Immunology·M SekiM Maeno
Oct 7, 2010·Journal of Dental Research·N Takahashi, B Nyvad
Jan 10, 2012·International Journal of Paediatric Dentistry·Mitsugi OkadaHidemi Kurihara

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Citations

Apr 28, 2016·Journal of Applied Oral Science : Revista FOB·Simonetta D'ErcoleDomenico Tripodi
Jun 16, 2016·Brazilian Oral Research·Ana Paula Vasques Sales BraúnaLia Silva de Castilho
Dec 3, 2016·Brazilian Oral Research·Esra Uzer CelikBilge Hakan Sen
Dec 13, 2016·Applied and Environmental Microbiology·Jianye ZhouZhiqiang Li
Nov 12, 2016·Applied and Environmental Microbiology·Ian B StanawayElaine M Faustman
Aug 6, 2020·Journal of Functional Biomaterials·Rayan B YaghmoorAnne M Young
May 24, 2019·Journal of Intellectual Disability Research : JIDR·L M WardD Kinnear
Oct 6, 2020·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Mark Achtman, Zhemin Zhou

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Datasets Mentioned

BETA
M75035

Methods Mentioned

BETA
enzyme-linked immunosorbent assays
PCR
electrophoresis

Software Mentioned

SPSS

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