Longitudinal study of neuropsychological functioning in patients on chronic hemodialysis: a preliminary report
This study is part of a five-year project to investigate the long term effect of chronic hemodialysis on patients with end-stage renal failure. Previous research has associated hemodialysis with progressive dialysis encephalopathy (PDE), which is characterized by speech disturbances, cognitive impairment, myoclonus and behavioral changes. Little is known about the cause or the course of this syndrome except that it begins 14-36 months after treatment onset and usually culminates in death. The purpose of this study was to investigate neuropsychological (cognitive and behavioral) functioning in dialysis patients over a period of years. To date, 34 patients have been studied for 22 months utilizing a cross-sectional method comparing patients at different stages of treatment combined with a longitudinal method of repeated evaluations over time. Current findings show improved cognitive functioning during at least the first year of treatment and no evidence of cognitive deterioration in patients on dialysis for more than one year (M = 4.3). These findings offer strong evidence that PDE is not necessarily a general phenomenon among patients on chronic hemodialysis.
A prospective study of patients in chronic hemodialysis-III. Predictive value of intelligence, cognitive deficit and ego defence structures in rehabilitation
Relationship of dialysis modality and other factors to cognitive function in chronic dialysis patients
Contingent negative variation before and after hemodialysis among patients with end-stage renal disease
Cognition in People With End-Stage Kidney Disease Treated With Hemodialysis: A Systematic Review and Meta-analysis
The effects of dialysis modality choice on cognitive functions in patients with end-stage renal failure: a systematic review and meta-analysis.
Abnormal rich club organization in end-stage renal disease patients before dialysis initiation and undergoing maintenance hemodialysis.
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