PMID: 11316620Apr 24, 2001Paper

Longitudinal study of quality of life in people with advanced Alzheimer's disease

The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry
S M AlbertY Stern

Abstract

The authors examined three indicators of health-related quality of life in people with advanced Alzheimer's disease ([AD]; N=150): confinement to home, null activity, and null positive affect, as reported by patient proxies. Dementia severity predicted time-to-onset for all three disease milestones in models that controlled for sociodemographic indicators, nursing home status, and death in the follow-up period. Patients whose dementia worsened over follow-up were more likely to reach each milestone. These outcomes represent key milestones in the care of patients; they are sensitive to disease progression, and they are likely to be useful for studying treatment in advanced AD.

References

Jun 1, 1982·The British Journal of Psychiatry : the Journal of Mental Science·C P HughesR L Martin
Jan 1, 1996·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·M P LawtonJ Klapper
Nov 1, 1996·Journal of the American Geriatrics Society·S M AlbertY Stern
Nov 3, 1997·PharmacoEconomics·G H Guyatt, R J Jaeschke
Jan 7, 1998·Journal of Aging and Health·D N KernerR M Kaplan

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Citations

May 2, 2007·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Kiran Rabheru
Jul 7, 2007·The Clinical Neuropsychologist·Jason Brandt
Apr 3, 2012·American Journal of Alzheimer's Disease and Other Dementias·Aine M Ní MhaoláinBrian Lawlor
Dec 28, 2002·American Journal of Alzheimer's Disease and Other Dementias·Raymond B Flannery
Jun 24, 2004·Journal of the American Geriatrics Society·Marlene A ReimerMichael Eliasziw
Apr 4, 2003·International Journal of Geriatric Psychiatry·Constantine G LyketsosPeter Rabins
Jul 4, 2006·Lifetime Data Analysis·Zhezhen JinZhiliang Ying
Sep 15, 2006·Journal of the American Geriatrics Society·Catherine E DubeauJohn N Morris
Nov 30, 2006·International Journal of Geriatric Psychiatry·Carla J M Schölzel-DorenbosRose-Marie Dröes
Feb 18, 2005·International Journal of Geriatric Psychiatry·Amber SelwoodMartin Orrell
Apr 14, 2007·Canadian Journal on Aging = La Revue Canadienne Du Vieillissement·Susan Slaughter, Jane Bankes
May 16, 2007·International Journal of Geriatric Psychiatry·Pierre MissottenOvide Fontaine
Jan 24, 2008·International Journal of Geriatric Psychiatry·Pierre MissottenOvide Fontaine
Jul 19, 2005·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Teake P EttemaMiel W Ribbe
Jan 8, 2010·International Journal of Geriatric Psychiatry·Siegfried WeyererIngrid Hendlmeier
Nov 26, 2009·Alzheimer Disease and Associated Disorders·Pierre MissottenMichel Ylieff
Mar 24, 2016·International Psychogeriatrics·P MissottenS Adam
Jan 26, 2013·International Psychogeriatrics·Jaime PeralesCarol Brayne
Aug 13, 2010·International Psychogeriatrics·Antonis A MougiasVenetsanos G Mavreas
Jul 6, 2010·American Journal on Intellectual and Developmental Disabilities·Tiina K UrvWayne Silverman
May 25, 2016·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Yaakov SternOksana Tatarina
Aug 28, 2019·Research in Gerontological Nursing·Ann KolanowskiKaren Eshraghi
Feb 23, 2020·Zeitschrift für Gerontologie und Geriatrie·Barbara Steiner
Jul 9, 2011·Clinical Genetics·A K HoUNKNOWN European Huntington's Disease Network Quality of Life Working Group

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