Longitudinal study on goiter prevalence and goitrogen factors in northeastern Sicily

Journal of Endocrinological Investigation
C RegalbutoRiccardo Vigneri

Abstract

A longitudinal study was carried out in an area of endemic goiter of north-eastern Sicily. Three different surveys (in 1977, 1983 and 1994) evaluated the epidemiological prevalence of goiter in schoolchildren of the endemic area (towns of Bronte, Troina and Maniaci) in comparison to an iodine sufficient control area (Catania). Biochemical studies were also performed on urinary iodine and thiocyanate (SCN) excretion and 131I thyroid uptake. In the town of Troina an experimental program of active iodine prophylaxis was carried out from 1979 to 1987 by iodinating the municipal water supply. The aim of this study was to evaluate the effect of an active iodine prophylaxis program in comparison to the "silent iodoprophylaxis" due to improved economic conditions and widespread introduction of industrially produced food. In the 1977-94 period a significant decrease of goiter prevalence in schoolchildren was observed in all areas where no active iodoprophylaxis had been introduced. An abnormal prevalence of goiter, however, was still present in Bronte (12.1%) and Maniaci (25.9%) schoolchildren in respect to Catania (0.7%). In Troina, goiter prevalence decreased from 52.2 to 6.1% after only five years of active iodine prophylaxis (1983)....Continue Reading

References

Apr 1, 1978·The Journal of Clinical Endocrinology and Metabolism·P BourdouxA M Ermans
Apr 1, 1978·Journal of Endocrinological Investigation·F DelangeA M Ermans
Aug 1, 1986·The Journal of Clinical Endocrinology and Metabolism·S SquatritoS H Ingbar
Jan 11, 1985·Deutsche medizinische Wochenschrift·R GutekunstP C Scriba
Apr 1, 1984·The Journal of Clinical Endocrinology and Metabolism·S B ChristensenA Melander
Jul 1, 1984·The Journal of Clinical Endocrinology and Metabolism·L SavaR Vigneri
Feb 1, 1983·The Journal of Clinical Endocrinology and Metabolism·A BelfioreR Vigneri
Oct 9, 1981·Deutsche medizinische Wochenschrift·J BrunnP C Scriba
Jul 1, 1981·Journal of Endocrinological Investigation·S SquatritoR Vigneri
Aug 1, 1994·The Journal of Clinical Endocrinology and Metabolism·P VittiG Araneo
Jan 1, 1964·Clinica Chimica Acta; International Journal of Clinical Chemistry·N S CONSTANTSAS, C DANELATOU-ATHANASSIADOU
Jan 1, 1964·Clinica Chimica Acta; International Journal of Clinical Chemistry·G M WIDDOWSON, B E NORTHAM
Dec 1, 1945·The Analyst·V J ALBERICCI

❮ Previous
Next ❯

Citations

Dec 4, 2009·Journal of Endocrinological Investigation·C RegalbutoV Pezzino
Feb 12, 2002·Asia-Pacific Journal of Public Health·C YamadaT Umenai
May 6, 1999·American Journal of Physical Anthropology·R CiranniG Fornaciari
Apr 11, 2008·Thyroid : Official Journal of the American Thyroid Association·Salvatore Benvenga, Francesco Trimarchi
Feb 22, 2007·Clinical Chemistry and Laboratory Medicine : CCLM·Giuseppe StellaJean-Louis Guéant
Sep 4, 1999·Journal of Endocrinological Investigation·G LupoliV Macchia
Nov 10, 2005·The British Journal of Nutrition·Venanzio Vella

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved