Longitudinal trends in antiretroviral use in a cohort of men and women in Ontario, Canada

AIDS Patient Care and STDs
Michelle D FurlerReina Bendayan

Abstract

Initial studies have shown impaired access to antiretrovirals and slower adoption of new therapies by women. It is unclear if similar treatment delays still occur, especially in those with a publicly funded health care system in Ontario, Canada. The objectives of this study were (1) to evaluate longitudinal patterns of antiretroviral use in patients with HIV in Ontario and (2) to determine if gender differences exist in access to and uptake of antiretroviral drugs over time. A retrospective medical chart review was undertaken. One hundred four HIV-positive patients were recruited from nine hospital-based HIV outpatient clinics throughout Ontario. From time of study enrollment in 1999-2001 to the first clinic visit (8.1 +/- 3.2 years; range, 2.3-16.8 years), CD4+ T-cell counts, date of and agents used in initial antiretroviral regimen, and first HAART regimen were evaluated by gender. Kaplan-Meier plots were used to evaluate time to drug initiation from known HIV diagnosis. Serial cross sections of numbers and types of antiretroviral drugs prescribed in March, June, September, and December 1988 to 2001 were also compared as was number of regimens used. There were few differences between men and women in antiretroviral use; both ...Continue Reading

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Jan 6, 2005·AIDS Patient Care and STDs·Michelle D FurlerReina Bendayan
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Citations

Jun 28, 2007·AIDS Patient Care and STDs·David EisenmanWilliam Cunningham
May 24, 2007·AIDS Patient Care and STDs·Patricia BragaAluisio Cotrim Segurado
Feb 22, 2012·International Journal of Epidemiology·Sean B RourkeAnita Rachlis
Jun 24, 2008·The Journal of Antimicrobial Chemotherapy·Inmaculada Jiménez-NácherVincent Soriano
Jun 14, 2013·Transactions of the Royal Society of Tropical Medicine and Hygiene·Adrián Alejandro FaríasViviana Elizabeth Ré
Jul 16, 2010·Journal of Midwifery & Women's Health·Carole A Lunny, Shawn N Fraser

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