PMID: 9556169Apr 29, 1998Paper

Longterm survey (7 years) in a population at risk for Lyme borreliosis: what happens to the seropositive individuals?

European Journal of Epidemiology
H FahrerL E Gern

Abstract

In 1986, a 26% seroprevalence of IgG- anti-Borrelia burgdorferi antibodies was observed among 950 orienteers and the incidence of new clinical infections was 0.8%. In 1993, a total of 305 seropositive orienteers were reexamined. During that time, 15 cases (4.9%) of definite/probable Lyme disease occurred in this seropositive group (12 skin manifestations and 3 monoarticular joint manifestations). Among the 12 definite cases, 9 showed new clinical infections (7 EM, 1 acrodermatitis chronica atrophicans, 1 arthritis), and 3 were recurrent (2 EM, 1 arthritis). The annual incidence (0.8%) in this seropositive group was identical to the incidence observed among the whole population in 1986. The individual antibody titer decreased slightly but the seroreversion rate was low (7%). Serology was not very helpful in identifying clinical cases and evolutions, and it can be stated, that a positive serology is much more frequent in this risk group than clinical disease.

Citations

Mar 15, 2011·Vector Borne and Zoonotic Diseases·Meagan F Vaughn, Steven R Meshnick
Feb 22, 2017·Emerging Infectious Diseases·Jessica L HallRichard J Birtles
Dec 25, 2010·Srpski arhiv za celokupno lekarstvo·Natasa ColovićMilica Colović
Dec 21, 2019·Indian Journal of Ophthalmology·Parthopratim Dutta Majumder
Jun 9, 2020·Frontiers in Cellular and Infection Microbiology·Emilie Talagrand-ReboulCarole Eldin
Jul 2, 2019·Médecine et maladies infectieuses·X GockoUNKNOWN endorsed by the following scientific societies

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