Loops on loops: generation of complex scaffolded peptides presenting multiple cyclic fragments

Organic & Biomolecular Chemistry
Raimo FrankeJ Eichler


Scaffolded peptides presenting two different cyclic peptide fragments through a cyclic peptidomimetic scaffold in a site-selective fashion, were generated by stepwise solid phase synthesis and fragment condensation in parallel, demonstrating that either strategy is adequate to generate complex scaffolded peptides.


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Related Concepts

High Pressure Liquid Chromatography Procedure
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