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Loss of MHC and neutral variation in Peary caribou: genetic drift is not mitigated by balancing selection or exacerbated by MHC allele distributions

PloS One

Jun 2, 2012

Sabrina S TaylorPeter Arcese

Abstract

Theory and empirical results suggest that the rate of loss of variation at Mhc and neutral microsatellite loci may differ because selection influences Mhc genes, and because a high proportion of rare alleles at Mhc loci may result in high rates of loss via drift. Most published studies ...read more

Mentioned in this Paper

Genetic Drift
Short Tandem Repeat
Ethanol
Polymerase
Ethanol Measurement
Dysequilibrium Syndrome
Wolves
Codon, Terminator
Recombination, Genetic
Gene Amplification Technique
Paper Details
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Loss of MHC and neutral variation in Peary caribou: genetic drift is not mitigated by balancing selection or exacerbated by MHC allele distributions

PloS One

Jun 2, 2012

Sabrina S TaylorPeter Arcese

PMID: 22655029

DOI: 10.1371/journal.pone.0036748

Abstract

Theory and empirical results suggest that the rate of loss of variation at Mhc and neutral microsatellite loci may differ because selection influences Mhc genes, and because a high proportion of rare alleles at Mhc loci may result in high rates of loss via drift. Most published studies ...read more

Mentioned in this Paper

Genetic Drift
Short Tandem Repeat
Ethanol
Polymerase
Ethanol Measurement
Dysequilibrium Syndrome
Wolves
Codon, Terminator
Recombination, Genetic
Gene Amplification Technique

Feeds With Similar Papers

Structure and Function of DNA

The double helix structure of DNA is important for its biological function. Discover the latest research on the Structure and Function of DNA here.

HLA Genetic Variation

HLA genetic variation has been found to confer risk for a wide variety of diseases. Identifying these associations and understanding their molecular mechanisms is ongoing and holds promise for the development of therapeutics. Find the latest research on HLA genetic variation here.

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Paper Details
References
  • References50
  • Citations10
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