Loss of muscle mass: a significant predictor of postoperative complications in acute diverticulitis

The Journal of Surgical Research
Kazuhide MatsushimaDemetrios Demetriades

Abstract

Severe muscle mass depletion, sarcopenia, has been shown to be associated with poor operative outcomes. However, its impact on emergency abdominal operations remains unclear. The purpose of this study was to examine the association between low muscle mass (LMM) and outcomes after emergency operations for acute diverticulitis. Patients ≥18 y requiring an emergency operation for acute diverticulitis between January 2007 and September 2014 were included. On preoperative computed tomography, the cross-sectional area (CSA) and transverse diameter (TVD) of the right and left psoas muscle were measured at the level of the third lumbar vertebral body. Sensitivity analysis was performed to determine appropriate CSA and TVD cutoff values defining low skeletal muscle mass. Clinical outcomes of patients with low muscle mass (LMM group) were compared with the non-LMM group. A total of 89 patients met our inclusion criteria. Median CSA and TVD were 794 mm2 and 24 mm, respectively. There was a strong correlation between the CSA and TVD (R2 = 0.84). In univariable analysis, significantly higher rates of postoperative major complications (63% versus 37%, P = 0.027) and surgical site infection (47% versus 19%, P = 0.008) were identified in the L...Continue Reading

Citations

Mar 21, 2019·Current Opinion in Anaesthesiology·David G A WilliamsPaul E Wischmeyer
Jun 4, 2020·Anaesthesia and Intensive Care·Patrick R JoyceChristopher Anstey
Jul 1, 2017·Current Opinion in Critical Care·Paul E WischmeyerMichael P W Grocott

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