Loss to follow-up and bias assessment among a cohort of Thai men who have sex with men in Bangkok, Thailand

International Journal of STD & AIDS
Sarika PattanasinTimothy H Holtz

Abstract

Minimising loss to follow-up is essential to obtain unbiased results. This study aimed to assess factors associated with loss to follow-up and effects on biasing exposure-outcome associations in a cohort of men who have sex with men in Bangkok. We enrolled sexually-active Thai men who have sex with men, at least 18 years old, in a study with four-monthly follow-up visits. At each visit, men answered HIV risk behaviour questions using audio computer-assisted self-interview. Logistic regression was used to evaluate factors associated with loss to follow-up and bias between exposures and prevalent HIV infection were estimated using adjusted relative odds ratios. From 2006 to 2010, we enrolled 1744 men who have sex with men; as of April, 2014, 1256 (72%) had completed at least the month-36 visit; loss to follow-up was 9.6%. Factors independently associated with loss to follow-up were age (18-21 years), education (primary level or less, secondary or vocational education), living outside Bangkok and vicinity, sexual orientation (bisexual, heterosexual), previous HIV testing, HIV infection, and behaviour in the past 4 months (recreational drug use, reporting group sex). An effect of loss to follow-up on factors of prevalent HIV infect...Continue Reading

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Citations

Dec 15, 2018·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Rebecca G NowakManhattan E Charurat
Oct 27, 2018·International Journal of STD & AIDS·Eileen F DunneTimothy H Holtz
Nov 28, 2018·BMC Medical Research Methodology·Samantha TeagueUNKNOWN SEED Lifecourse Sciences Theme
Apr 2, 2020·International Journal of STD & AIDS·Sarika PattanasinEileen F Dunne
Jun 6, 2019·Ciência & saúde coletiva·Simone Souza MonteiroRichard Parker
Aug 1, 2020·Journal of Acquired Immune Deficiency Syndromes : JAIDS·August EubanksUNKNOWN CohMSM-PrEP Study Group

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Methods Mentioned

BETA
Nucleic Acid Amplification
enzyme-linked immunosorbent assay

Software Mentioned

STATA®

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