Low- q Bicelles Are Mixed Micelles

The Journal of Physical Chemistry Letters
Tracy A CaldwellLinda Columbus

Abstract

Bicelles are used in many membrane protein studies because they are thought to be more bilayer-like than micelles. We investigated the properties of "isotropic" bicelles by small-angle neutron scattering, small-angle X-ray scattering, fluorescence anisotropy, and molecular dynamics. All data suggest that bicelles with a q value below 1 deviate from the classic bicelle that contains lipids in the core and detergent in the rim. Thus not all isotropic bicelles are bilayer-like.

References

Dec 15, 1978·Biochimica Et Biophysica Acta·M Shinitzky, Y Barenholz
Aug 28, 1984·Biochemistry·N E Gabriel, M F Roberts
Feb 1, 1996·Journal of Molecular Graphics·W HumphreyK Schulten
Oct 22, 1998·Structure·C R Sanders, R S Prosser
Jul 27, 2001·Biochimica Et Biophysica Acta·P A LuchetteJ Katsaras
Mar 19, 2003·Bioorganic Chemistry·Jennifer A WhilesEdward A Dennis
Nov 3, 2004·Biochimica Et Biophysica Acta·Annela M SeddonPaula J Booth
Jan 1, 2005·Biophysical Journal·Mohamed N TribaPhilippe F Devaux
Feb 4, 2005·Protein Science : a Publication of the Protein Society·Salem FahamJames U Bowie
Feb 10, 2006·Journal of Molecular Biology·Thorsten LührsKurt Wüthrich
Jul 11, 2006·Magnetic Resonance in Chemistry : MRC·Mandar V DeshmukhHorst Kessler
Oct 11, 2007·The Journal of Physical Chemistry. B·Jan LipfertSebastian Doniach
May 12, 2009·Journal of the American Chemical Society·Linda ColumbusScott A Lesley
Apr 12, 2011·Biochimica Et Biophysica Acta·Dror E WarschawskiIsabelle Marcotte
Jan 20, 2012·Journal of Visualized Experiments : JoVE·Rachna Ujwal, Jeff Abramson
Mar 8, 2013·Progress in Nuclear Magnetic Resonance Spectroscopy·Ulrich H N DürrAyyalusamy Ramamoorthy
May 7, 2014·Langmuir : the ACS Journal of Surfaces and Colloids·Maïwenn BeaugrandIsabelle Marcotte
Jul 22, 2014·Chembiochem : a European Journal of Chemical Biology·He TianThomas Huber
Oct 15, 2014·Langmuir : the ACS Journal of Surfaces and Colloids·Ryan C OliverLinda Columbus
Dec 17, 2014·Journal of Magnetic Resonance·Jesse E McCaffreyDavid D Thomas
Jan 8, 2015·Langmuir : the ACS Journal of Surfaces and Colloids·Kazutoshi YamamotoAyyalusamy Ramamoorthy
Mar 6, 2015·Journal of the American Society for Mass Spectrometry·Nguyen Minh DucKa Young Chung
May 8, 2015·Methods in Enzymology·Sandra PoulosSalem Faham
Mar 20, 2016·Journal of Molecular Biology·Peter Y MercrediMichael F Summers
Jun 11, 2016·Langmuir : the ACS Journal of Surfaces and Colloids·K S MineevA S Arseniev
Oct 18, 2016·Chemistry : a European Journal·Alessandro PiaiJames J Chou

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Citations

Apr 12, 2020·Angewandte Chemie·Evan S O'BrienA Joshua Wand
Sep 26, 2019·The Journal of Biological Chemistry·Robbins Puthenveetil, Olga Vinogradova
Jul 5, 2019·Nature Protocols·Qingshan FuJames J Chou
Oct 21, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Andrew J Y JonesDaniel Nietlispach
Aug 11, 2019·Biochimica Et Biophysica Acta. Biomembranes·Erik K LarsenGianluigi Veglia
Nov 2, 2019·Biochimica Et Biophysica Acta. Biomembranes·E F DudásA Bodor
Dec 25, 2019·Biochimica Et Biophysica Acta. Biomembranes·Rhiannon L Brooks, Ann M Dixon
Jan 19, 2020·Biochimica Et Biophysica Acta. Biomembranes·Mary HernandoJoe D O'Neil
Aug 11, 2021·Journal of the American Chemical Society·Rama K KoppisettiSteven R Van Doren
Jun 25, 2020·Journal of the American Chemical Society·James M HutchisonCharles R Sanders
Apr 21, 2020·Langmuir : the ACS Journal of Surfaces and Colloids·Tun Naw SutNam-Joon Cho
Sep 8, 2021·Biochemistry·Courtney L Labrecque, Brian Fuglestad

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