PMID: 8608286Mar 30, 1996Paper

Low blood pressure and dementia in elderly people: the Kungsholmen project

BMJ : British Medical Journal
Z GuoB Winblad

Abstract

To examine the relation between blood pressure and dementia in elderly people. Cross sectional, population based study. Kungsholmen district of Stockholm, Sweden. 1642 subjects aged 75-101 years. Prevalence and adjusted odds ratio of dementia by blood pressure. People with systolic pressure < or = 140 mm Hg were more often diagnosed as demented than those with systolic pressure >140 mm Hg: odds ratios (95% confidence interval) adjusted for age, sex, and education were 2.98 (2.17 to 4.08) for all dementias, 2.91 (1.93 to 4.38) for Alzheimer's disease, 2.00 (1.09 to 3.65) for vascular dementia, and 5.07 (2.65 to 9.70) for other dementias. Similar results were seen in subjects with diastolic pressure < or = 75 mm Hg compared with those with higher diastolic pressure. When severity and duration of dementia were taken into account, only moderate and severe dementia were found to be significantly related to relatively low blood pressure, and the association was stronger in subjects with longer disease duration. Use of hypotensive drugs and comorbidity with cardiovascular disease did not modify the results for all dementias, Alzheimer's disease, and other dementias but slightly reduced the association between vascular dementia and dia...Continue Reading

References

Jun 1, 1978·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·H E Nelson, A O'Connell
Sep 1, 1975·Archives of Neurology·V C HachinskiL Symon
Dec 1, 1992·Journal of Neurology, Neurosurgery, and Psychiatry·J T O'BrienR Levy
Jun 22, 1991·BMJ : British Medical Journal·C M van Duijn, A Hofman
Jan 1, 1991·Alzheimer Disease and Associated Disorders·W D Brown, R S Frackowiak
Oct 2, 1987·JAMA : the Journal of the American Medical Association·G C Román
Aug 1, 1987·Acta Neurologica Scandinavica·R Sulkava, T Erkinjuntti
Jun 1, 1982·The British Journal of Psychiatry : the Journal of Mental Science·C P HughesR L Martin
Aug 20, 1994·Lancet·S Strandgaard, O B Paulson
Jun 1, 1994·Journal of the Autonomic Nervous System·W J BurkeH D Chung
May 1, 1994·Dementia·M D O'Brien
Jan 1, 1994·Stroke; a Journal of Cerebral Circulation·R H Ackerman, M R Candia

❮ Previous
Next ❯

Citations

Dec 12, 2007·Archives of Neurology·Christiane ReitzJosé A Luchsinger
Sep 1, 2003·Environmental Health and Preventive Medicine·Junko Okuno, Hisako Yanagi
Jun 16, 2004·Aging Clinical and Experimental Research·Mervi Kähönen-VäreReijo Tilvis
Apr 19, 2005·Der Internist·A Hartmann, S Moskau
Sep 21, 2004·Der Nervenarzt·R Scheid, H Voigt
May 10, 2006·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Hannah C HeimsLisa Cipolotti
Dec 6, 2001·Current Hypertension Reports·A S RigaudF Forette
Jan 3, 2006·Current Hypertension Reports·Ihab HajjarBrandy Frost
Jun 14, 2005·La Revue de médecine interne·V Antoine, A-S Rigaud
Nov 6, 2002·Journal of the Neurological Sciences·Gustavo C Román
Jun 1, 2002·Ageing Research Reviews·Lenore J Launer
Apr 27, 1996·Lancet·I SkoogA Svanborg
Jan 13, 2001·Archives of Gerontology and Geriatrics·A AlgotssonB Winblad
Sep 18, 2004·Archives of Gerontology and Geriatrics·E LondosL Gustafson
May 5, 2000·Neurobiology of Aging·L J LaunerR J Havlik
Jun 27, 2000·Neurobiology of Aging·T KudoM Takeda
May 30, 2001·Neurobiology of Aging·T Szili-TörökL Rudas
Jul 14, 2001·Journal of the American College of Cardiology·K KarioS Wassertheil-Smoller
Jan 1, 1997·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Z GuoB Winblad
Jan 1, 1997·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·I Skoog
Nov 1, 2003·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Robert N DavisRachelle S Doody
Jul 10, 2003·Lancet Neurology·Gustavo C RománHelena C Chui
Jul 29, 2010·Journal of the International Neuropsychological Society : JINS·Jeannette R MahoneyRoee Holtzer
Apr 13, 2001·Journal of the American Geriatrics Society·R StewartA Mann
Jun 10, 2006·Scandinavian Journal of Public Health. Supplement·Kristina Larsson, Mats Thorslund
Nov 15, 2000·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·R T SchaubE Steinhagen-Thiessen
May 5, 2000·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·M C MorrisD A Evans
Apr 3, 2001·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·A S Rigaud, B Forette
Feb 28, 2002·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Ha T NguyenKyriakos S Markides
Mar 20, 2004·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Reijo S TilvisTimo E Strandberg
Jul 20, 2011·QJM : Monthly Journal of the Association of Physicians·A DuthieR L Soiza
Jun 15, 2006·Alzheimer Disease and Associated Disorders·Kathleen M HaydenUNKNOWN Cache County Investigators
Dec 14, 2002·Annals of the New York Academy of Sciences·Masatoshi Fujishima, Yutaka Kiyohara
Mar 30, 1996·BMJ : British Medical Journal·J M Pearce
Jul 13, 1996·BMJ : British Medical Journal·V P Prasher, J A Blair
Dec 18, 2012·Cardiovascular Psychiatry and Neurology·Jack C de la Torre
Feb 23, 2012·Dementia and Geriatric Cognitive Disorders·Mehmet Emin KuyumcuServet Arıoğul
Jul 1, 2009·Hypertension·Robert StewartLenore J Launer
Sep 17, 2011·American Journal of Alzheimer's Disease and Other Dementias·Yuan-Han YangJohn C Morris
Oct 3, 2002·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Rie Hakamada-TaguchiTeruhiko Toyo-oka
Sep 23, 2010·Vascular Health and Risk Management·Suzanne A LigthartEdo Richard
Jul 22, 2004·Neurological Research·Gustavo C Román

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.