Apr 4, 2020

Multi-dimensional tuning in motor cortical neurons during active behavior

BioRxiv : the Preprint Server for Biology
Rachel C Yuan, Sarah W Bottjer

Abstract

A region within songbird cortex, AId (dorsal intermediate arcopallium), is functionally analogous to motor cortex in mammals and has been implicated in vocal learning during development. AId thus serves as a powerful model for investigating motor cortical contributions to developmental skill learning. We made extracellular recordings in AId of freely behaving juvenile zebra finches and evaluated neural activity during diverse motor behaviors throughout entire recording sessions, including song production as well as hopping, pecking, preening, fluff-ups, beak interactions with cage objects, scratching, and stretching. A large population of single neurons showed significant modulation of activity during singing relative to quiescence. In addition, AId neurons demonstrated heterogeneous response patterns that were evoked during multiple movements, with single neurons often demonstrating excitation during one movement type and suppression during another. Lesions of AId do not disrupt vocal motor output or impair generic movements, suggesting that the responses observed during active behavior do not reflect direct motor drive. Consistent with this idea, we found that some AId neurons showed differential activity during pecking movem...Continue Reading

  • References
  • Citations

References

  • We're still populating references for this paper, please check back later.
  • References
  • Citations

Citations

  • This paper may not have been cited yet.

Mentioned in this Paper

Genetic Drift
Biological Markers
Size
Research
Salmo salar
Nucleic Acid Hybridization Procedure
Salmon
Genetic Markers
Cell Differentiation Process
Salmon allergenic extract

Related Feeds

BioRxiv & MedRxiv Preprints

BioRxiv and MedRxiv are the preprint servers for biology and health sciences respectively, operated by Cold Spring Harbor Laboratory. Here are the latest preprint articles (which are not peer-reviewed) from BioRxiv and MedRxiv.

Cell Migration

Cell migration is involved in a variety of physiological and pathological processes such as embryonic development, cancer metastasis, blood vessel formation and remoulding, tissue regeneration, immune surveillance and inflammation. Here is the latest research.

Related Papers

BioRxiv : the Preprint Server for Biology
Anthony W AzevedoJohn C Tuthill
Journal of Neurophysiology
Keri L PageThomas Matheson
Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology
Ari Berkowitz
© 2020 Meta ULC. All rights reserved