Low cholesterol level as a risk marker of inpatient and post-discharge violence in acute psychiatry - A prospective study with a focus on gender differences

Psychiatry Research
Bjørn Magne S EriksenJ O Roaldset

Abstract

Several studies indicate an association between low levels of serum cholesterol and aggressive behaviour, but prospective studies are scarce. In this naturalistic prospective inpatient and post-discharge study from an acute psychiatric ward, we investigated total cholesterol (TC) and high-density lipoprotein (HDL) as risk markers of violence. From March 21, 2012, to March 20, 2013, 158 men and 204 women were included. TC and HDL were measured at admission. Violence was recorded during hospital stay and for the first 3 months post-discharge. Univariate and multivariate binary logistic regression were used to estimate associations between low TC and low HDL and violence. Results showed that HDL level was significantly inversely associated with violence during hospital stay for all patients. For men, but not for women, HDL level was significantly inversely associated with violence the first 3 months post-discharge. Results indicate that low HDL is a risk marker for inpatient and post-discharge violence in acute psychiatry and also suggest gender differences in HDL as a risk marker for violence.

References

May 1, 1997·Psychiatric Services : a Journal of the American Psychiatric Association·K TardiffL Portera
Mar 22, 2000·Psychiatry Research·L Buydens-BrancheyP Fergeson
Dec 6, 2000·Journal of Psychiatric Research·B A GolombS Mednick
Mar 22, 2003·European Psychiatry : the Journal of the Association of European Psychiatrists·J VeveraH Papezová
Oct 17, 2003·Psychiatry Research·Flavio PozziGaetano Frajese
Jul 20, 2004·BMJ : British Medical Journal·Jonathan J Deeks, Douglas G Altman
Jan 8, 2005·Acta Psychiatrica Scandinavica·H L I NijmanJ J Stolker
Jul 16, 2005·Psychiatric Services : a Journal of the American Psychiatric Association·John MonahanEric Silver
Feb 4, 2006·Journal of Psychiatric Research·Alfonso Troisi, Alberto D'Argenio
Mar 2, 2006·The British Journal of Psychiatry : the Journal of Mental Science·Kimberlie DeanTom Fahy
May 3, 2006·Archives of General Psychiatry·Jeffrey W SwansonJeffrey A Lieberman
Mar 19, 2008·The American Journal of Psychiatry·Larry J Siever
Feb 19, 2009·Progress in Neuro-psychopharmacology & Biological Psychiatry·Bernard Wallner, Ivo H Machatschke
May 16, 2009·Psychology, Health & Medicine·Gerdi WeidnerWilliam E Connor
May 12, 2010·European Psychiatry : the Journal of the Association of European Psychiatrists·P HartvigS Bjørkly
Jul 14, 2010·European Psychiatry : the Journal of the Association of European Psychiatrists·J O RoaldsetS Bjørkly
Jun 4, 2013·Journal of Clinical Lipidology·Frances M SahebzamaniKevin E Kip
Feb 8, 2014·Psychiatry Research·Peter AsellusJussi Jokinen
Aug 19, 2014·Law and Human Behavior·Jay P SinghUNKNOWN RAGEE Group
Dec 4, 2014·Metabolism: Clinical and Experimental·Madhu Kalia, Jorge Costa E Silva
May 26, 2015·Journal of Psychiatric Research·Shing-Chia ChenWei J Chen

❮ Previous
Next ❯

Citations

Nov 12, 2019·Psychological Science·Erika M Manczak, Ian H Gotlib
Dec 4, 2019·Acta Neuropsychiatrica·Katrin Tomson-JohansonJaanus Harro
Apr 8, 2018·European Psychiatry : the Journal of the Association of European Psychiatrists·Taanvi RameshSeena Fazel
Jan 20, 2018·Current Opinion in Endocrinology, Diabetes, and Obesity·Katrin Tomson-Johanson, Jaanus Harro
Apr 27, 2021·The Journal of Steroid Biochemistry and Molecular Biology·Wassim GuidaraFatma Ayadi
Jul 10, 2021·The Australian and New Zealand Journal of Psychiatry·Piyal SenVeena Kumari

❮ Previous
Next ❯

Related Concepts

Related Feeds

ApoE, Lipids & Cholesterol

Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.