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Low concentrations of methamidophos do not alter AChE activity but modulate neurotransmitters uptake in hippocampus and striatum in vitro

Life Sciences

Jan 3, 2011

Priscila GubertFélix Alexandre Antunes Soares

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Abstract

Methamidophos (Meth) is a toxic organophosphorus compound (OP) that inhibits acetylcholinesterase enzyme (AChE) and induces neurotoxicity. As the mechanism of its neurotoxic effects is not well understood, the aim of the present study was to evaluate the effects of Meth on glutamate and...read more

Mentioned in this Paper

Acetylcholine
Acetylcholinesterase
Acetylthiocholinesterase
Adenosine Triphosphatases
Na(+)-K(+)-Exchanging ATPase
Angiotensin-Converting Enzyme Inhibitors
Axon
Blood - Brain Barrier Anatomy
Brain
Catecholamines
Paper Details
References
  • References42
  • Citations5
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Low concentrations of methamidophos do not alter AChE activity but modulate neurotransmitters uptake in hippocampus and striatum in vitro

Life Sciences

Jan 3, 2011

Priscila GubertFélix Alexandre Antunes Soares

PMID: 21075126

DOI: 10.1016/j.lfs.2010.10.031

Abstract

Methamidophos (Meth) is a toxic organophosphorus compound (OP) that inhibits acetylcholinesterase enzyme (AChE) and induces neurotoxicity. As the mechanism of its neurotoxic effects is not well understood, the aim of the present study was to evaluate the effects of Meth on glutamate and...read more

Mentioned in this Paper

Acetylcholine
Acetylcholinesterase
Acetylthiocholinesterase
Adenosine Triphosphatases
Na(+)-K(+)-Exchanging ATPase

Similar Papers Found In These Feeds

Related Papers

Paper Details
References
  • References42
  • Citations5
12345

Get paper from

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