Low concentrations of monosodium glutamate (MSG) are safe in male Drosophila melanogaster

BMC Research Notes
Keneth Iceland KasoziAlfred Omachonu Okpanachi

Abstract

Monosodium glutamate (MSG) has been marred by a lot of controversy on its safety. In a majority of experimental studies, administration of the compound has been parenteral, and yet little is known about MSG safety consumed as a food supplement. In this study, we assessed the effects of low concentrations of MSG on the activity of hydrogen scavenging, catalase activity and climbing as well as lifespan in male Drosophila melanogaster over a 30 days period since this has been sparsely studied. No significant differences were associated with MSG at 5%, 1%, 0.2%, 0.04% on hydrogen peroxide scavenging, negative geotaxis and lifespan in W1118 male D. melanogaster. Significant differences were found in 5% MSG on catalase activity, showing that high MSG concentrations would affect tissue health in male D. melanogaster. MSG consumed as a food supplement would be safe at concentrations below 5% MSG.

References

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Citations

May 10, 2020·Journal of Complementary & Integrative Medicine·Emmanuel Tiyo AyikobuaMiriam Nansunga
May 16, 2019·BMC Research Notes·Keneth Iceland KasoziMuhamudu Kalange

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