Low contrast dose voiding urosonography in children with phase inversion imaging

European Radiology
Andrea KopitzkoThomas Albrecht

Abstract

Voiding urosonography (VUS) using a microbubble contrast agent has been introduced as an alternative technique in the diagnosis of vesicoureteral reflux (VUR). This study was undertaken to assess if phase inversion ultrasound (PIUS), a recent microbubble specific imaging technique, has advantages over fundamental in VUS and if it allows a reduction of contrast agent dose. Forty-three children with suspected VUR (aged 3 days-12 years, average of 3.9 years) with 92 kidney-ureter units (KUU) were included. Everyone obtained a baseline US scan that was followed by VUS using Levovist as the contrast agent. Constant switching between fundamental and PIUS performed the enhanced part for comparison. Every child underwent VCUG immediately afterwards. Contrast enhancement was stronger and longer lasting on PIUS than on fundamental US in all 43 cases. Reflux was detected in a total of 21 KUU, out of 92 KUU (23%). PIUS revealed VUR in 18; fundamental in 14 KUU and VCUG depicted 16 cases of reflux (p> or =0.29). The mean volume of Levovist dose administered to the bladder was 7.4+/-3.4% of the bladder volume. VUS using PI mode provided considerably stronger and longer enhancement and slightly improved the detection of VUR. It allowed a redu...Continue Reading

References

Dec 1, 1976·British Journal of Urology·R N TremewanJ J Tait
Aug 1, 1975·Archives of Disease in Childhood·J M Smellie, I C Normand
May 1, 1991·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·B S Arant
May 1, 1994·Klinische Pädiatrie·G AlzenF J Deutz
Nov 1, 1996·The Journal of Urology·H N Noe
Oct 1, 1996·Scandinavian Journal of Urology and Nephrology·M SaragaV Marković
Feb 2, 2000·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·C PolitoR Di Toro
Nov 22, 2001·AJR. American Journal of Roentgenology·K DargeJ Troeger
Jan 17, 2002·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Kassa Darge
Mar 1, 2002·European Radiology·Frederica PapadopoulouAnastasia Economou
Apr 17, 2002·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Hans-Joachim MentzelWerner A Kaiser
Jul 20, 2002·European Journal of Radiology·Kassa Darge, Jochen Troeger
Jul 2, 2003·European Radiology·Alejandro MatéMaria José Bello

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Related Feeds

Bladder Carcinoma In Situ

Bladder Carcinoma In Situ is a superficial bladder cancer that occurs on the surface layer of the bladder. Discover the latest research on this precancerous condition in this feed.