Low contrast vision function predicts subsequent acuity loss in an aged population: the SKI study

Vision Research
M SchneckGinny Gildengorin

Abstract

Can vision tests predict subsequent loss of acuity? The association between performance on several low contrast spatial vision measures, glare recovery, color discrimination, flicker sensitivity, stereopsis and ocular disease status at baseline and acuity loss 4.4 years later was examined in a large aged random sample with good initial acuity. In univariate analyses, several vision measures, retinal disease status and age were each significant predictors of subsequent acuity loss. In a multiple regression analysis, only low contrast spatial vision was a significant predictor, but the other vision measures, retinal disease status and age were not. For each doubling of low contrast spatial vision threshold at baseline, individuals were more than two times as likely to suffer subsequent significant visual acuity loss. Tests of low contrast spatial vision are strong predictors of significant subsequent visual acuity loss. These findings have implications for clinical trials, clinical management, and acceptance of these measures into clinical practice.

References

Nov 1, 1976·American Journal of Optometry and Physiological Optics·I L Bailey, J E Lovie
Jun 1, 1992·Ophthalmology·R KleinK L Linton
Dec 1, 1991·Optometry and Vision Science : Official Publication of the American Academy of Optometry·I L Bailey, M A Bullimore
Aug 1, 1991·Ophthalmology·R KleinD L De Mets
Feb 1, 1990·Archives of Ophthalmology·J M TielschR M Royall
Jan 1, 1990·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·S Pardhan, J Gilchrist
Jan 1, 1986·Experimental Gerontology·N S Gittings, J L Fozard
Jul 1, 1986·American Journal of Optometry and Physiological Optics·M M Spafford, J V Lovasik
Jan 1, 1983·Vision Research·C OwsleyD Siemsen
Jan 1, 1981·Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Albrecht Von Graefe's Archive for Clinical and Experimental Ophthalmology·L Frisén, M Frisén
Mar 1, 1995·Optometry and Vision Science : Official Publication of the American Academy of Optometry·D B ElliottD Whitaker
Mar 1, 1995·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·D ReedE Schneider
Aug 1, 1993·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·R CagenelloD L Halpern
Apr 23, 1999·Optometry and Vision Science : Official Publication of the American Academy of Optometry·G Haegerstrom-PortnoyJ A Brabyn
Jan 9, 2001·Optometry and Vision Science : Official Publication of the American Academy of Optometry·G Haegerstrom-PortnoyJ A Brabyn
Nov 26, 2003·Investigative Ophthalmology & Visual Science·Peter N DimitrovHugh R Taylor

❮ Previous
Next ❯

Citations

May 28, 2013·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Darren E KoenigRaymond A Applegate
Aug 30, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Gesa Astrid HahnSusanne Trauzettel-Klosinski
Nov 1, 2005·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Jan Lovie-Kitchin, Beatrix Feigl
Oct 25, 2007·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Zahra JessaGill Rowlands
Sep 16, 2011·International Journal of Geriatric Psychiatry·Jason C S LeungP C Leung
Feb 18, 2017·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Andrew Carkeet, Ian L Bailey
Feb 16, 2005·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Gunilla Haegerstrom-Portnoy
May 25, 2010·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Lei Liu, Janis White
Jul 6, 2014·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Lei LiuHarold E Bedell
Jun 19, 2013·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Daniel R CoatesSusana T L Chung
Nov 15, 2017·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Angelica LyMichael Kalloniatis

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.