PMID: 9636215Jun 24, 1998Paper

Low dimensionality of supraspinally induced force fields

Proceedings of the National Academy of Sciences of the United States of America
A d'Avella, E Bizzi

Abstract

Recent experiments using electrical and N-methyl-D-aspartate microstimulation of the spinal cord gray matter and cutaneous stimulation of the hindlimb of spinalized frogs have provided evidence for a modular organization of the frog's spinal cord circuitry. A "module" is a functional unit in the spinal cord circuitry that generates a specific motor output by imposing a specific pattern of muscle activation. The output of a module can be characterized as a force field: the collection of the isometric forces generated at the ankle over different locations in the leg's workspace. Different modules can be combined independently so that their force fields linearly sum. The goal of this study was to ascertain whether the force fields generated by the activation of supraspinal structures could result from combinations of a small number of modules. We recorded a set of force fields generated by the electrical stimulation of the vestibular nerve in seven frogs, and we performed a principal component analysis to study the dimensionality of this set. We found that 94% of the total variation of the data is explained by the first five principal components, a result that indicates that the dimensionality of the set of fields evoked by vestib...Continue Reading

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Citations

Apr 23, 2013·Experimental Brain Research·Christoph Schütz, Thomas Schack
Apr 24, 2001·Neural Networks : the Official Journal of the International Neural Network Society·J J Slotine, W Lohmiller
Dec 23, 1999·Current Opinion in Neurobiology·F A Mussa-Ivaldi
Sep 16, 2005·Nature·Leslie C OsborneWilliam Bialek
Mar 9, 2011·Proceedings of the National Academy of Sciences of the United States of America·Greg J StephensWilliam Bialek
Sep 19, 2008·Journal of Neurophysiology·Jason J KutchWilliam Z Rymer
Apr 5, 2008·PLoS Computational Biology·Greg J StephensWilliam S Ryu
Nov 26, 2010·PloS One·Greg J StephensWilliam S Ryu
Dec 1, 2009·Human Movement Science·Till BockemühlVolker Dürr
Jun 6, 2009·IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·Michel A LemayWarren M Grill
Apr 8, 2004·IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·Y AoyagiA Prochazka
Nov 23, 2006·Neuron·Reinhard Gentner, Joseph Classen
Jun 7, 2014·Frontiers in Human Neuroscience·Thomas SchackDirk Koester
Oct 14, 2016·Scientific Reports·Vittorio CaggianoEmilio Bizzi
Sep 9, 2016·PLoS Computational Biology·Kang HeKunlin Wei
Apr 9, 1999·Nature Neuroscience·M C TreschE Bizzi
Mar 17, 2001·Nature Reviews. Neuroscience·E BizziA d'Avella
Oct 31, 2002·Nature Neuroscience·Emanuel Todorov, Michael I Jordan
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Apr 30, 2004·Journal of Neurophysiology·Elizabeth Garcia-PerezVincent Torre
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Oct 17, 2020·Proceedings of the National Academy of Sciences of the United States of America·Amit YaronKazuhiko Seki
Dec 5, 2017·Human Movement Science·Vitor L S Profeta, Michael T Turvey

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