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Low-dose cidofovir and conversion to mTOR-based immunosuppression in polyomavirus-associated nephropathy (PVAN)

Transplant Infectious Disease : an Official Journal of the Transplantation Society

Dec 5, 2019

Thomas MühlbacherMartina Guthoff

Abstract

Polyomavirus-associated nephropathy (PVAN) remains a relevant complication following kidney transplantation with allograft loss rates of up to 50%. Reduction of overall immunosuppression is a cornerstone of therapy, whereas no specific antiviral regimen has shown conclusive benefit to d...read more

Mentioned in this Paper

Nephrotoxicity
Virus
Follow-up
Mtor Signaling Pathway BioCarta
Antigens, Polyomavirus Transforming
Transplantation
Therapeutic Immunosuppression
Complication
Plasma
Antiviral Therapy
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Low-dose cidofovir and conversion to mTOR-based immunosuppression in polyomavirus-associated nephropathy (PVAN)

Transplant Infectious Disease : an Official Journal of the Transplantation Society

Dec 5, 2019

Thomas MühlbacherMartina Guthoff

PMID: 31797495

DOI: 10.1111/tid.13228

Abstract

Polyomavirus-associated nephropathy (PVAN) remains a relevant complication following kidney transplantation with allograft loss rates of up to 50%. Reduction of overall immunosuppression is a cornerstone of therapy, whereas no specific antiviral regimen has shown conclusive benefit to d...read more

Mentioned in this Paper

Nephrotoxicity
Virus
Follow-up
Mtor Signaling Pathway BioCarta
Antigens, Polyomavirus Transforming
Transplantation
Therapeutic Immunosuppression
Complication
Plasma
Antiviral Therapy

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Paper Details
References
  • References25
  • Citations
123
  • References25
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