Low-dose mirtazapine may be successful treatment option for severe nausea and vomiting

Progress in Neuro-psychopharmacology & Biological Psychiatry
Chi-Un Pae

Abstract

The antagonism of 5-HT3 receptor by mirtazapine results in an antiemetic effect, suggesting that mirtazapine could be considered a successful antiemetic agent in patients suffering from severe nausea and vomiting. There have been several reports of successful mirtazapine treatment for nausea or vomiting from secondary causes but cases of primary severe nausea and vomiting are still lacking, in particular, there are no reported cases in Asians. The authors report two cases with severe nausea and vomiting that were dramatically treated with mirtazapine in the Korean population.

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Citations

Feb 22, 2008·Psychiatry and Clinical Neurosciences·Sung-Wan KimJin-Sang Yoon
Oct 12, 2011·Journal of Veterinary Internal Medicine·J M QuimbyK F Lunn
Apr 24, 2010·Journal of Pain and Symptom Management·Mellar P DavisUNKNOWN Palliative Medicine Study Group of the Multinational Association of Supportive Care in Cancer
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Sep 1, 2015·The Australian and New Zealand Journal of Psychiatry·Swapna BondadeNiharika Singh
Jan 15, 2021·Current Treatment Options in Oncology·Janet Hardy, Mellar P Davis

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