Low energy availability, not stress of exercise, alters LH pulsatility in exercising women

Journal of Applied Physiology
A B LoucksE M Heath

Abstract

We tested two hypotheses about the disruption of luteinizing hormone (LH) pulsatility in exercising women by assaying LH in blood samples drawn at 10-min intervals over 24 h from nine young, habitually sedentary, regularly menstruating women on days 8, 9, or 10 of two menstrual cycles after 4 days of intense exercise [E = 30 kcal.kg lean body mass (LBM)-1.day-1 at 70% of aerobic capacity]. To test the hypothesis that LH pulsatility is disrupted by low energy availability, we controlled the subjects' dietary energy intakes (I) to set their energy availabilities (A = I - E) at 45 and 10 kcal.kg LBM-1.day-1 during the two trials. To test the hypothesis that LH pulsatility is disrupted by the stress of exercise, we compared the resulting LH pulsatilities to those previously reported in women with similar controlled energy availability who had not exercised. In the exercising women, low energy availability reduced LH pulse frequency by 10% (P < 0.01) during the waking hours and increased LH pulse amplitude by 36% (P = 0.05) during waking and sleeping hours, but this reduction in LH pulse frequency was blunted by 60% (P = 0.03) compared with that in the previously studied nonexercising women whose low energy availability was caused b...Continue Reading

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Citations

Dec 12, 2001·Sports Medicine·D C Cumming, C E Cumming
Mar 19, 2002·Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquée·A B Loucks
Oct 17, 2002·Journal of Applied Physiology·Gretchen A CasazzaGeorge A Brooks
May 17, 2003·Medicine and Science in Sports and Exercise·Kristin L CobbJennifer L Kelsey
Mar 6, 2004·Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquée·Vicki J Harber
Sep 3, 2004·The New England Journal of Medicine·Corrine K WeltChristos S Mantzoros
Oct 1, 2005·Endocrinology·Marla E LujanDean A Van Vugt
Apr 26, 2006·The American Journal of Sports Medicine·Mark F Reinking
May 5, 2006·Medicine and Science in Sports and Exercise·Anne B Loucks
Feb 3, 2007·Obstetrics and Gynecology·Anne B LoucksNancy I Williams
Aug 25, 2007·Journal of Applied Physiology·Anne B Loucks
Nov 6, 2007·Current Opinion in Endocrinology, Diabetes, and Obesity·Anne B Loucks
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