Low fitness is associated with metabolic risk independently of central adiposity in a cohort of 18-year-olds

Scandinavian Journal of Medicine & Science in Sports
E LättJ Mäestu

Abstract

It is unclear whether cardiorespiratory fitness (CRF) remains associated with metabolic risk if controlled for central adiposity and other confounders; thus, the aim of this study was to investigate the independent effect of CRF on metabolic syndrome risk factors in relatively homogeneous age group of young adults. In this cross-sectional study, 828 participants performed CRF test on a cycle ergometer (Wmax kg ) and were categorized into sex-specific tertiles. Continuous metabolic syndrome risk score (MetS-score) was calculated as the sum of standardized scores of five metabolic syndrome risk factors: glucose, mean arterial pressure, low-density lipoprotein cholesterol, triglycerides, and total cholesterol/high-density lipoprotein cholesterol ratio. Low fitness group had higher values in all measured metabolic syndrome parameters, except for cholesterol parameters, compared to high fitness group. The unadjusted model indicated that CRF was negatively associated with clustered metabolic risk (β = -0.116, P = .001). After the adjustment of smoking habits, sports training participation, and waist circumference, the association between CRF and MetS-score slightly increased (β = -0.126; P < .001). Low CRF was associated with increas...Continue Reading

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Citations

Aug 31, 2021·Frontiers in Physiology·Paulo GentilDaniel Souza

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