Abstract
Folic acid deficiency is implicated in the aetiology of nutritional anaemia and adverse pregnancy outcomes for the fetus. Data on folic acid status among adolescent girls and non-pregnant, non-lactating young women are limited. We assessed folic acid status in a random sample of 552 subjects (277 adolescent girls aged 15-18.9 years and 275 women aged 19-30 years) living in Colombo, Sri Lanka. The association of low folic acid status with anaemia was evaluated. Socio-economic, food intake and anthropometric data were obtained. Hb, serum folic acid, vitamin B12 and ferritin and plasma homocysteine concentrations were measured. Forty-three per cent of subjects studied had low serum folic acid concentrations (<3 ng/ml) and 47 % had low Fe stores (serum ferritin <20 microg/l). Overall prevalence of anaemia was 12.9 %, and 43.9 % of anaemic subjects had both low folic acid status and depleted Fe stores (serum ferritin <12 microg/l). Both low folate status and depleted Fe stores were significantly associated with anaemia (odds ratio = 2.32; 95 % CI 1.34, 4.01 and odds ratio = 5.98; 95 % CI 3.36, 10.63, respectively). Serum folic acid concentration was associated (r = 0.108, P = 0.015) with folate intake as indicated by a computed fola...Continue Reading
References
Apr 25, 1991·The New England Journal of Medicine·R ClarkeI Graham
Sep 1, 1987·The American Journal of Clinical Nutrition·V Herbert
Dec 1, 1995·Journal of the American Dietetic Association·C Ballew, S B Sugerman
May 1, 1994·Public Health·M M RahmanE Biswas
Feb 1, 1994·The American Journal of Clinical Nutrition·J L Beard
Jun 1, 1996·The Journal of Obstetrics and Gynaecology Research·L D de Silva, T M Atukorala
Dec 1, 1996·The Journal of Nutrition·K L TuckerI H Rosenberg
Jan 24, 1998·The Journal of Nutrition·M A CaudillL B Bailey
Nov 13, 1999·The New England Journal of Medicine·R J BerryA Correa
Jan 5, 2002·Lancet·N J WaldD S Wald
Sep 25, 2002·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·K GiskesB Newman
Feb 11, 2003·Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'obstétrique Et Gynécologie Du Canada : JOGC·Sarah D McDonaldMark C Walker
Mar 15, 2003·BMJ : British Medical Journal·Parul ChristianKeith P West
Mar 26, 2003·Annals of Nutrition & Metabolism·Esther CasanuevaStephen J Rothenberg
Jan 17, 2004·Lancet·UNKNOWN WHO Expert Consultation
Dec 2, 2004·Indian Journal of Pediatrics·Priyali PathakPreeti Singh
Citations
Aug 19, 2007·The British Journal of Nutrition·Katsuhiko YokoiJames G Penland
Jan 20, 2011·European Journal of Clinical Nutrition·Y BaY Zhang
Dec 13, 2007·Obesity Surgery·D J DaviesJ N Baxter
Nov 18, 2008·The Journal of Obstetrics and Gynaecology Research·Masayo MatsuzakiSachiyo Murashima
Apr 17, 2012·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·T ThoradeniyaP Lanerolle
Apr 29, 2016·The British Journal of Nutrition·Thamar A YilaReiko Kishi
Nov 21, 2017·PloS One·Angela AllenAnuja Premawardhena
Apr 3, 2019·Nutrients·Amara E EzeamamaWafaie W Fawzi
Sep 14, 2012·Public Health Nutrition·Iris IglesiaLuis A Moreno
Jul 19, 2019·The Journal of Nutrition·Abeer M AljaadiTim J Green
Oct 14, 2014·Public Health Nutrition·Deshanie RaiKaren M Chapman-Novakofski
Jun 1, 2019·European Journal of Clinical Nutrition·Rebecca L NunnCaroline H D Fall
Jul 3, 2020·European Journal of Nutrition·Miruna Sudharshani Kalaimani RabindrakumarTharanga Thoradeniya
Jan 11, 2017·BMC Public Health·N P G C R NaotunnaS B Agampodi
Jan 5, 2019·BMC Hematology·Miruna Sudharshani Kalaimani RabindrakumarTharanga Thoradeniya
Mar 25, 2017·Nutrition Reviews·Eva Almiron-RoigBasma Ellahi
Oct 31, 2018·Nutrients·Hansani Madushika AbeywickramaYuta Mitobe
Nov 19, 2018·Systematic Reviews·K M Saif-Ur-RahmanShariful Islam
Dec 22, 2020·Maternal & Child Nutrition·Radhika S MadhariLongvah Thingnganing
Jan 8, 2021·BMC Pediatrics·Kalaichelvi ThillanPujitha Wickramasinghe
Apr 17, 2021·Nutrition Research Reviews·Sara Estecha QuerolLena Al-Khudairy
Jul 9, 2021·BMC Public Health·Pradeep KumarDebashree Sinha