Low glycemic load experimental diet more satiating than high glycemic load diet.

Nutrition and Cancer
Kevin T ChangMarian L Neuhouser

Abstract

Effective strategies for reducing food intake are needed to reduce risk of obesity-related cancers. We investigated the effect of low and high glycemic load (GL) diets on satiety and whether satiety varied by body mass index (BMI), gender, and serum leptin. Eighty normal weight (BMI = 18.5-24.9 kg/m²) and overweight/ obese (BMI = 28.0-40.0 kg/m²) adults participated in a randomized, crossover controlled feeding study testing low GL vs. high GL diets. The 28-day diets were isocaloric with identical macronutrient distributions, differing only in GL and fiber. Participants completed visual analog satiety surveys and fasting serum leptin after each 28-day period. T-tests compared mean within- and between-person satiety scores and leptin values. Participants reported 7% greater satiation on the low GL vs. the high GL diet (P = 0.03) and fewer food cravings on the low GL vs. the high GL diet (P < 0.001). Compared to males, females reported less hunger (P = 0.05) and more satiety on the low GL vs. the high GL diet (P < 0.01). Participants with low body fat (<25.0% for men; <32.0% for women) and BMI <25.0 kg/m² reported study food was tastier on the low GL vs. the high GL diet (P = 0.04 and P = 0.05, respectively). In summary, reducing...Continue Reading

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Citations

May 24, 2016·Nutrients·Kevin B ComerfordStephanie A Atkinson
Jan 19, 2016·Molecular Nutrition & Food Research·Henry J ThompsonAnne McTiernan
Jun 2, 2017·Journal of Women's Health·Leah BrennanLisa Moran
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Methods Mentioned

BETA
X-ray
ELISA

Clinical Trials Mentioned

NCT00622661

Software Mentioned

SPSS

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